Galetin A - Search Results

1

Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug Interactions.

Willemin ME, Van Der Made TK, Pijpers I, Dillen L, Kunze A, Jonkers S, Steemans K, Tuytelaars A, Jacobs F, Monshouwer M, Scotcher D, Rostami-Hodjegan A, Galetin A, Snoeys J. Willemin ME, et al. Among authors: galetin a. Clin Pharmacokinet. 2021 Sep;60(9):1187-1199. doi: 10.1007/s40262-021-01004-2. Epub 2021 Apr 10. Clin Pharmacokinet. 2021. PMID: 33840062 Clinical Trial.

2

Prediction of in vivo drug-drug interactions from in vitro data : factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4.

Brown HS, Galetin A, Hallifax D, Houston JB. Brown HS, et al. Among authors: galetin a. Clin Pharmacokinet. 2006;45(10):1035-50. doi: 10.2165/00003088-200645100-00006. Clin Pharmacokinet. 2006. PMID: 16984215

3

Critique of the two-fold measure of prediction success for ratios: application for the assessment of drug-drug interactions.

Guest EJ, Aarons L, Houston JB, Rostami-Hodjegan A, Galetin A. Guest EJ, et al. Among authors: galetin a. Drug Metab Dispos. 2011 Feb;39(2):170-3. doi: 10.1124/dmd.110.036103. Epub 2010 Oct 29. Drug Metab Dispos. 2011. PMID: 21036951

4

Assessment of algorithms for predicting drug-drug interactions via inhibition mechanisms: comparison of dynamic and static models.

Guest EJ, Rowland-Yeo K, Rostami-Hodjegan A, Tucker GT, Houston JB, Galetin A. Guest EJ, et al. Among authors: galetin a. Br J Clin Pharmacol. 2011 Jan;71(1):72-87. doi: 10.1111/j.1365-2125.2010.03799.x. Br J Clin Pharmacol. 2011. PMID: 21143503 Free PMC article.

5

Evaluation of various static in vitro-in vivo extrapolation models for risk assessment of the CYP3A inhibition potential of an investigational drug.

Vieira ML, Kirby B, Ragueneau-Majlessi I, Galetin A, Chien JY, Einolf HJ, Fahmi OA, Fischer V, Fretland A, Grime K, Hall SD, Higgs R, Plowchalk D, Riley R, Seibert E, Skordos K, Snoeys J, Venkatakrishnan K, Waterhouse T, Obach RS, Berglund EG, Zhang L, Zhao P, Reynolds KS, Huang SM. Vieira ML, et al. Among authors: galetin a. Clin Pharmacol Ther. 2014 Feb;95(2):189-98. doi: 10.1038/clpt.2013.187. Epub 2013 Sep 18. Clin Pharmacol Ther. 2014. PMID: 24048277

6

PBPK models for the prediction of in vivo performance of oral dosage forms.

Kostewicz ES, Aarons L, Bergstrand M, Bolger MB, Galetin A, Hatley O, Jamei M, Lloyd R, Pepin X, Rostami-Hodjegan A, Sjögren E, Tannergren C, Turner DB, Wagner C, Weitschies W, Dressman J. Kostewicz ES, et al. Among authors: galetin a. Eur J Pharm Sci. 2014 Jun 16;57:300-21. doi: 10.1016/j.ejps.2013.09.008. Epub 2013 Sep 21. Eur J Pharm Sci. 2014. PMID: 24060672 Review.

7

The use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.

Olivares-Morales A, Hatley OJ, Turner D, Galetin A, Aarons L, Rostami-Hodjegan A. Olivares-Morales A, et al. Among authors: galetin a. Pharm Res. 2014 Mar;31(3):720-30. doi: 10.1007/s11095-013-1193-2. Epub 2013 Sep 27. Pharm Res. 2014. PMID: 24072264 Free PMC article.

8

Identification of the effect of multiple polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid using a population-modeling approach.

Tsamandouras N, Dickinson G, Guo Y, Hall S, Rostami-Hodjegan A, Galetin A, Aarons L. Tsamandouras N, et al. Among authors: galetin a. Clin Pharmacol Ther. 2014 Jul;96(1):90-100. doi: 10.1038/clpt.2014.55. Epub 2014 Mar 5. Clin Pharmacol Ther. 2014. PMID: 24598718

9

Development and Application of a Mechanistic Pharmacokinetic Model for Simvastatin and its Active Metabolite Simvastatin Acid Using an Integrated Population PBPK Approach.

Tsamandouras N, Dickinson G, Guo Y, Hall S, Rostami-Hodjegan A, Galetin A, Aarons L. Tsamandouras N, et al. Among authors: galetin a. Pharm Res. 2015 Jun;32(6):1864-83. doi: 10.1007/s11095-014-1581-2. Epub 2014 Dec 2. Pharm Res. 2015. PMID: 25446771 Clinical Trial.

10

Meta-analysis of expression of hepatic organic anion-transporting polypeptide (OATP) transporters in cellular systems relative to human liver tissue.

Badée J, Achour B, Rostami-Hodjegan A, Galetin A. Badée J, et al. Among authors: galetin a. Drug Metab Dispos. 2015 Apr;43(4):424-32. doi: 10.1124/dmd.114.062034. Epub 2015 Jan 6. Drug Metab Dispos. 2015. PMID: 25564656

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