Tang W - Search Results

1

Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor.

Rao D, Li H, Ren X, Sun Y, Wen C, Zheng M, Huang H, Tang W, Xu S. Rao D, et al. Among authors: tang w. Eur J Med Chem. 2021 Jul 5;219:113393. doi: 10.1016/j.ejmech.2021.113393. Epub 2021 Mar 30. Eur J Med Chem. 2021. PMID: 33845236

2

Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.

Cheng XC, Wang Q, Fang H, Tang W, Xu WF. Cheng XC, et al. Among authors: tang w. Bioorg Med Chem. 2008 May 15;16(10):5398-404. doi: 10.1016/j.bmc.2008.04.027. Epub 2008 Apr 15. Bioorg Med Chem. 2008. PMID: 18440232

3

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors.

Chao B, Tong XK, Tang W, Li DW, He PL, Garcia JM, Zeng LM, Gao AH, Yang L, Li J, Nan FJ, Jacobs M, Altmeyer R, Zuo JP, Hu YH. Chao B, et al. Among authors: tang w. J Med Chem. 2012 Apr 12;55(7):3135-43. doi: 10.1021/jm2015952. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22448770

4

Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.

Deng J, Li N, Liu H, Zuo Z, Liew OW, Xu W, Chen G, Tong X, Tang W, Zhu J, Zuo J, Jiang H, Yang CG, Li J, Zhu W. Deng J, et al. Among authors: tang w. J Med Chem. 2012 Jul 26;55(14):6278-93. doi: 10.1021/jm300146f. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22742496

5

Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.

Ye D, Shin WJ, Li N, Tang W, Feng E, Li J, He PL, Zuo JP, Kim H, Nam KY, Zhu W, Seong BL, No KT, Jiang H, Liu H. Ye D, et al. Among authors: tang w. Eur J Med Chem. 2012 Aug;54:764-70. doi: 10.1016/j.ejmech.2012.06.033. Epub 2012 Jun 29. Eur J Med Chem. 2012. PMID: 22795831

6

Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors.

Feng E, Shin WJ, Zhu X, Li J, Ye D, Wang J, Zheng M, Zuo JP, No KT, Liu X, Zhu W, Tang W, Seong BL, Jiang H, Liu H. Feng E, et al. Among authors: tang w. J Med Chem. 2013 Feb 14;56(3):671-84. doi: 10.1021/jm3009713. Epub 2013 Jan 30. J Med Chem. 2013. PMID: 23330908

7

Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.

Kang S, Tang W, Li H, Chreifi G, Martásek P, Roman LJ, Poulos TL, Silverman RB. Kang S, et al. Among authors: tang w. J Med Chem. 2014 May 22;57(10):4382-96. doi: 10.1021/jm5004182. Epub 2014 May 7. J Med Chem. 2014. PMID: 24758147 Free PMC article.

8

Structure-based design of bacterial nitric oxide synthase inhibitors.

Holden JK, Kang S, Hollingsworth SA, Li H, Lim N, Chen S, Huang H, Xue F, Tang W, Silverman RB, Poulos TL. Holden JK, et al. Among authors: tang w. J Med Chem. 2015 Jan 22;58(2):994-1004. doi: 10.1021/jm501723p. Epub 2015 Jan 6. J Med Chem. 2015. PMID: 25522110 Free PMC article.

9

2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.

Kang S, Li H, Tang W, Martásek P, Roman LJ, Poulos TL, Silverman RB. Kang S, et al. Among authors: tang w. J Med Chem. 2015 Jul 23;58(14):5548-60. doi: 10.1021/acs.jmedchem.5b00573. Epub 2015 Jul 10. J Med Chem. 2015. PMID: 26120733 Free PMC article.

10

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Hu J, Wang X, Chen L, Huang M, Tang W, Zuo J, Liu YC, Shi Z, Liu R, Shen J, Xiong B. Hu J, et al. Among authors: tang w. Bioorg Med Chem Lett. 2016 Feb 1;26(3):721-725. doi: 10.1016/j.bmcl.2016.01.006. Epub 2016 Jan 7. Bioorg Med Chem Lett. 2016. PMID: 26776360

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