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Page 1
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Moradi S, Stankovic S, O'Connor GM, Pymm P, MacLachlan BJ, Faoro C, Retière C, Sullivan LC, Saunders PM, Widjaja J, Cox-Livingstone S, Rossjohn J, Brooks AG, Vivian JP. Moradi S, et al. Among authors: pymm p. Nat Commun. 2021 Apr 12;12(1):2173. doi: 10.1038/s41467-021-22359-x. Nat Commun. 2021. PMID: 33846289 Free PMC article.
Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.
O'Connor GM, Vivian JP, Gostick E, Pymm P, Lafont BA, Price DA, Rossjohn J, Brooks AG, McVicar DW. O'Connor GM, et al. Among authors: pymm p. J Virol. 2015 May;89(10):5213-21. doi: 10.1128/JVI.03586-14. Epub 2015 Mar 4. J Virol. 2015. PMID: 25740999 Free PMC article.
The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.
Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP. Moradi S, et al. Among authors: pymm p. J Biol Chem. 2015 Apr 17;290(16):10460-71. doi: 10.1074/jbc.M114.612291. Epub 2015 Mar 10. J Biol Chem. 2015. PMID: 25759384 Free PMC article.
Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.
Saunders PM, Pymm P, Pietra G, Hughes VA, Hitchen C, O'Connor GM, Loiacono F, Widjaja J, Price DA, Falco M, Mingari MC, Moretta L, McVicar DW, Rossjohn J, Brooks AG, Vivian JP. Saunders PM, et al. Among authors: pymm p. J Exp Med. 2016 May 2;213(5):791-807. doi: 10.1084/jem.20152023. Epub 2016 Apr 4. J Exp Med. 2016. PMID: 27045007 Free PMC article.
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP. Pymm P, et al. Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20. Nat Struct Mol Biol. 2017. PMID: 28218747 Free PMC article.
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.
Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M. Martin MP, et al. Among authors: pymm p. J Clin Invest. 2018 May 1;128(5):1903-1912. doi: 10.1172/JCI98463. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29461980 Free PMC article. Clinical Trial.
30 results