Neamati N - Search Results

1

A Review of Small-Molecule Inhibitors of One-Carbon Enzymes: SHMT2 and MTHFD2 in the Spotlight.

Cuthbertson CR, Arabzada Z, Bankhead A 3rd, Kyani A, Neamati N. Cuthbertson CR, et al. Among authors: neamati n. ACS Pharmacol Transl Sci. 2021 Mar 1;4(2):624-646. doi: 10.1021/acsptsci.0c00223. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860190 Free PMC article. Review.

2

Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition.

Madak JT, Cuthbertson CR, Chen W, Showalter HD, Neamati N. Madak JT, et al. Among authors: neamati n. Chemistry. 2017 Oct 9;23(56):13875-13878. doi: 10.1002/chem.201702999. Epub 2017 Sep 12. Chemistry. 2017. PMID: 28833638 Free article.

3

Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer.

Tamura S, Wang Y, Veeneman B, Hovelson D, Bankhead A 3rd, Broses LJ, Lorenzatti Hiles G, Liebert M, Rubin JR, Day KC, Hussain M, Neamati N, Tomlins S, Palmbos PL, Grivas P, Day ML. Tamura S, et al. Among authors: neamati n. Bladder Cancer. 2018 Jan 20;4(1):77-90. doi: 10.3233/BLC-170144. Bladder Cancer. 2018. PMID: 29430509 Free PMC article.

4

Current Challenges and Opportunities in Treating Glioblastoma.

Shergalis A, Bankhead A 3rd, Luesakul U, Muangsin N, Neamati N. Shergalis A, et al. Among authors: neamati n. Pharmacol Rev. 2018 Jul;70(3):412-445. doi: 10.1124/pr.117.014944. Pharmacol Rev. 2018. PMID: 29669750 Free PMC article.

5

Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase.

Madak JT, Cuthbertson CR, Miyata Y, Tamura S, Petrunak EM, Stuckey JA, Han Y, He M, Sun D, Showalter HD, Neamati N. Madak JT, et al. Among authors: neamati n. J Med Chem. 2018 Jun 28;61(12):5162-5186. doi: 10.1021/acs.jmedchem.7b01862. Epub 2018 May 14. J Med Chem. 2018. PMID: 29727569 Free PMC article.

6

Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer.

Madak JT, Bankhead A 3rd, Cuthbertson CR, Showalter HD, Neamati N. Madak JT, et al. Among authors: neamati n. Pharmacol Ther. 2019 Mar;195:111-131. doi: 10.1016/j.pharmthera.2018.10.012. Epub 2018 Oct 19. Pharmacol Ther. 2019. PMID: 30347213 Review.

7

Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes.

Xu S, Liu Y, Yang K, Wang H, Shergalis A, Kyani A, Bankhead A 3rd, Tamura S, Yang S, Wang X, Wang CC, Rehemtulla A, Ljungman M, Neamati N. Xu S, et al. Among authors: neamati n. Theranostics. 2019 Apr 12;9(8):2282-2298. doi: 10.7150/thno.30621. eCollection 2019. Theranostics. 2019. PMID: 31149044 Free PMC article.

8

Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3.

Lu T, Bankhead A 3rd, Ljungman M, Neamati N. Lu T, et al. Among authors: neamati n. Theranostics. 2019 Jul 28;9(19):5478-5496. doi: 10.7150/thno.33444. eCollection 2019. Theranostics. 2019. PMID: 31534498 Free PMC article.

9

Role of the ERO1-PDI interaction in oxidative protein folding and disease.

Shergalis AG, Hu S, Bankhead A 3rd, Neamati N. Shergalis AG, et al. Among authors: neamati n. Pharmacol Ther. 2020 Jun;210:107525. doi: 10.1016/j.pharmthera.2020.107525. Epub 2020 Mar 20. Pharmacol Ther. 2020. PMID: 32201313 Free PMC article. Review.

10

Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor.

Xu Y, Bankhead A 3rd, Tian X, Tang J, Ljungman M, Neamati N. Xu Y, et al. Among authors: neamati n. Cancer Res. 2020 Sep 1;80(17):3692-3705. doi: 10.1158/0008-5472.CAN-20-0530. Epub 2020 Jun 22. Cancer Res. 2020. PMID: 32571799 Free PMC article.

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