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Species Difference in Hydrolysis of an Ester-Type Prodrug of Levodopa in Human and Animal Plasma: Different Contributions of Alpha-1 Acid Glycoprotein.
Kono K, Nunoya KI, Nakamura Y, Bi J, Mukunoki A, Takeo T, Nakagata N, Maeda H, Yamaura Y, Imawaka H, Watanabe H, Maruyama T. Kono K, et al. Among authors: yamaura y. Mol Pharm. 2022 Sep 5;19(9):3450. doi: 10.1021/acs.molpharmaceut.2c00598. Epub 2022 Jul 28. Mol Pharm. 2022. PMID: 35900112 No abstract available.
A Human Immortalized Cell-Based Blood-Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug-Brain Permeability Studies.
Ito R, Umehara K, Suzuki S, Kitamura K, Nunoya KI, Yamaura Y, Imawaka H, Izumi S, Wakayama N, Komori T, Anzai N, Akita H, Furihata T. Ito R, et al. Among authors: yamaura y. Mol Pharm. 2019 Nov 4;16(11):4461-4471. doi: 10.1021/acs.molpharmaceut.9b00519. Epub 2019 Oct 15. Mol Pharm. 2019. PMID: 31573814
Predicting successful/unsuccessful extrapolation for in vivo total clearance of model compounds with a variety of hepatic intrinsic metabolism and protein bindings in humans from pharmacokinetic data using chimeric mice with humanised liver.
Sawada T, Yamaura Y, Higuchi S, Imawaka H, Yamazaki H. Sawada T, et al. Among authors: yamaura y. Xenobiotica. 2020 May;50(5):526-535. doi: 10.1080/00498254.2019.1664791. Epub 2019 Sep 13. Xenobiotica. 2020. PMID: 31491346
Robust physiologically based pharmacokinetic model of rifampicin for predicting drug-drug interactions via P-glycoprotein induction and inhibition in the intestine, liver, and kidney.
Asaumi R, Nunoya KI, Yamaura Y, Taskar KS, Sugiyama Y. Asaumi R, et al. Among authors: yamaura y. CPT Pharmacometrics Syst Pharmacol. 2022 Jul;11(7):919-933. doi: 10.1002/psp4.12807. Epub 2022 Jun 6. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35570332 Free PMC article.
Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
Takayama K, Negoro R, Yamashita T, Kawai K, Ichikawa M, Mori T, Nakatsu N, Harada K, Ito S, Yamada H, Yamaura Y, Hirata K, Ishida S, Mizuguchi H. Takayama K, et al. Among authors: yamaura y. Cell Mol Gastroenterol Hepatol. 2019;8(3):513-526. doi: 10.1016/j.jcmgh.2019.06.004. Epub 2019 Jun 19. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31228606 Free PMC article.
129 results