Tomlinson S - Search Results

1

Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration.

Annamalai B, Parsons N, Nicholson C, Joseph K, Coughlin B, Yang X, Jones BW, Tomlinson S, Rohrer B. Annamalai B, et al. Among authors: tomlinson s. Exp Eye Res. 2021 Jun;207:108583. doi: 10.1016/j.exer.2021.108583. Epub 2021 Apr 18. Exp Eye Res. 2021. PMID: 33878326 Free PMC article.

2

A tumor-expressed inhibitor of the early but not late complement lytic pathway enhances tumor growth in a rat model of human breast cancer.

Caragine TA, Okada N, Frey AB, Tomlinson S. Caragine TA, et al. Among authors: tomlinson s. Cancer Res. 2002 Feb 15;62(4):1110-5. Cancer Res. 2002. PMID: 11861390

3

Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer.

Imai M, Landen C, Ohta R, Cheung NK, Tomlinson S. Imai M, et al. Among authors: tomlinson s. Cancer Res. 2005 Nov 15;65(22):10562-8. doi: 10.1158/0008-5472.CAN-05-1894. Cancer Res. 2005. PMID: 16288049

4

Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement.

Imai M, Ohta R, Varela JC, Song H, Tomlinson S. Imai M, et al. Among authors: tomlinson s. Cancer Res. 2007 Oct 1;67(19):9535-41. doi: 10.1158/0008-5472.CAN-07-1690. Cancer Res. 2007. PMID: 17909064

5

A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice.

Song H, Qiao F, Atkinson C, Holers VM, Tomlinson S. Song H, et al. Among authors: tomlinson s. J Immunol. 2007 Dec 1;179(11):7860-7. doi: 10.4049/jimmunol.179.11.7860. J Immunol. 2007. PMID: 18025232

6

Highly specific inhibition of C1q globular-head binding to human IgG: a novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable fragment.

Hwang HY, Duvall MR, Tomlinson S, Boackle RJ. Hwang HY, et al. Among authors: tomlinson s. Mol Immunol. 2008 May;45(9):2570-80. doi: 10.1016/j.molimm.2007.12.019. Epub 2008 Mar 3. Mol Immunol. 2008. PMID: 18313756 Free PMC article.

7

Modulation of protective T cell immunity by complement inhibitor expression on tumor cells.

Varela JC, Imai M, Atkinson C, Ohta R, Rapisardo M, Tomlinson S. Varela JC, et al. Among authors: tomlinson s. Cancer Res. 2008 Aug 15;68(16):6734-42. doi: 10.1158/0008-5472.CAN-08-0502. Cancer Res. 2008. PMID: 18701498 Free PMC article.

8

A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.

Huang Y, Qiao F, Atkinson C, Holers VM, Tomlinson S. Huang Y, et al. Among authors: tomlinson s. J Immunol. 2008 Dec 1;181(11):8068-76. doi: 10.4049/jimmunol.181.11.8068. J Immunol. 2008. PMID: 19017999 Free PMC article.

9

A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.

Rohrer B, Long Q, Coughlin B, Wilson RB, Huang Y, Qiao F, Tang PH, Kunchithapautham K, Gilkeson GS, Tomlinson S. Rohrer B, et al. Among authors: tomlinson s. Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3056-64. doi: 10.1167/iovs.08-2222. Epub 2009 Mar 5. Invest Ophthalmol Vis Sci. 2009. PMID: 19264882 Free PMC article.

10

Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury.

Thurman JM, Renner B, Kunchithapautham K, Ferreira VP, Pangburn MK, Ablonczy Z, Tomlinson S, Holers VM, Rohrer B. Thurman JM, et al. Among authors: tomlinson s. J Biol Chem. 2009 Jun 19;284(25):16939-16947. doi: 10.1074/jbc.M808166200. Epub 2009 Apr 21. J Biol Chem. 2009. PMID: 19386604 Free PMC article.

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