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Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
Singh N, Frey NV, Engels B, Barrett DM, Shestova O, Ravikumar P, Cummins KD, Lee YG, Pajarillo R, Chun I, Shyu A, Highfill SL, Price A, Zhao L, Peng L, Granda B, Ramones M, Lu XM, Christian DA, Perazzelli J, Lacey SF, Roy NH, Burkhardt JK, Colomb F, Damra M, Abdel-Mohsen M, Liu T, Liu D, Standley DM, Young RM, Brogdon JL, Grupp SA, June CH, Maude SL, Gill S, Ruella M. Singh N, et al. Among authors: chun i. Nat Med. 2021 May;27(5):842-850. doi: 10.1038/s41591-021-01326-5. Epub 2021 Apr 22. Nat Med. 2021. PMID: 33888899 Free PMC article. Clinical Trial.
Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer.
Lee YG, Guruprasad P, Ghilardi G, Pajarillo R, Sauter CT, Patel R, Ballard HJ, Hong SJ, Chun I, Yang N, Amelsberg KV, Cummins KD, Svoboda J, Gill S, Chong EA, North K, Church SE, Fraietta JA, Chang WJ, Lacey SF, Lu XM, Zhang Y, Whig K, Schultz DC, Cherry S, Gerson J, Schuster SJ, Porazzi P, Ruella M. Lee YG, et al. Among authors: chun i. Cancer Discov. 2022 Oct 5;12(10):2372-2391. doi: 10.1158/2159-8290.CD-21-1026. Cancer Discov. 2022. PMID: 35904479 Free PMC article.
Apoptosis: a Janus bifrons in T-cell immunotherapy.
Lee YG, Yang N, Chun I, Porazzi P, Carturan A, Paruzzo L, Sauter CT, Guruprasad P, Pajarillo R, Ruella M. Lee YG, et al. Among authors: chun i. J Immunother Cancer. 2023 Apr;11(4):e005967. doi: 10.1136/jitc-2022-005967. J Immunother Cancer. 2023. PMID: 37055217 Free PMC article. Review.
CD5 deletion enhances the antitumor activity of adoptive T cell therapies.
Patel RP, Ghilardi G, Zhang Y, Chiang YH, Xie W, Guruprasad P, Kim KH, Chun I, Angelos MG, Pajarillo R, Hong SJ, Lee YG, Shestova O, Shaw C, Cohen I, Gupta A, Vu T, Qian D, Yang S, Nimmagadda A, Snook AE, Siciliano N, Rotolo A, Inamdar A, Harris J, Ugwuanyi O, Wang M, Carturan A, Paruzzo L, Chen L, Ballard HJ, Blanchard T, Xu C, Abdel-Mohsen M, Gabunia K, Wysocka M, Linette GP, Carreno B, Barrett DM, Teachey DT, Posey AD, Powell DJ Jr, Sauter CT, Pileri S, Pillai V, Scholler J, Rook AH, Schuster SJ, Barta SK, Porazzi P, Ruella M. Patel RP, et al. Among authors: chun i. Sci Immunol. 2024 Jul 19;9(97):eadn6509. doi: 10.1126/sciimmunol.adn6509. Epub 2024 Jul 19. Sci Immunol. 2024. PMID: 39028827
Gaps and Similarities in Research Use LOINC Codes Utilized in Korean University Hospitals: Towards Semantic Interoperability for Patient Care.
Park K, Kim MS, Oh Y, Rim JH, Yu S, Ryu H, Cho EJ, Lee K, Kim HN, Chun I, Kwon A, Kim S, Chung JW, Chae H, Oh JS, Park HD, Kang M, Yun YM, Lim JB, Lee YK, Chun S. Park K, et al. Among authors: chun i. J Korean Med Sci. 2025 Jan 6;40(1):e4. doi: 10.3346/jkms.2025.40.e4. J Korean Med Sci. 2025. PMID: 39763308 Free PMC article.
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens.
Fenwick MK, Pierce PG, Abendroth J, Barrett KF, Barrett LK, Bowatte K, Choi R, Chun I, Conrady DG, Craig JK, Dranow DM, Hammerson B, Higgins T, Lorimer DD, Lukat P, Mayclin SJ, Hewitt SN, Peng YP, Shanbhogue A, Smutney H, Stigliano MZZ, Tillery LM, Udell HS, Wallace EG, DeRocher AE, Phan IQ, Staker BL, Subramanian S, Van Voorhis WC, Blankenfeldt W, Müller R, Edwards TE, Myler PJ. Fenwick MK, et al. Among authors: chun i. Commun Biol. 2024 Dec 5;7(1):1622. doi: 10.1038/s42003-024-07175-5. Commun Biol. 2024. PMID: 39639052 Free PMC article.
117 results