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A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters.
Zhang BZ, Wang X, Yuan S, Li W, Dou Y, Poon VK, Chan CC, Cai JP, Chik KK, Tang K, Chan CC, Hu YF, Hu JC, Badea SR, Gong HR, Lin X, Chu H, Li X, To KK, Liu L, Chen Z, Hung IF, Yuen KY, Chan JF, Huang JD. Zhang BZ, et al. Among authors: chen z. Emerg Microbes Infect. 2021 Dec;10(1):874-884. doi: 10.1080/22221751.2021.1921621. Emerg Microbes Infect. 2021. PMID: 33890550 Free PMC article.
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics.
Kao RY, Tsui WH, Lee TS, Tanner JA, Watt RM, Huang JD, Hu L, Chen G, Chen Z, Zhang L, He T, Chan KH, Tse H, To AP, Ng LW, Wong BC, Tsoi HW, Yang D, Ho DD, Yuen KY. Kao RY, et al. Among authors: chen z, chen g. Chem Biol. 2004 Sep;11(9):1293-9. doi: 10.1016/j.chembiol.2004.07.013. Chem Biol. 2004. PMID: 15380189 Free PMC article.
Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus.
Liu L, Fang Q, Deng F, Wang H, Yi CE, Ba L, Yu W, Lin RD, Li T, Hu Z, Ho DD, Zhang L, Chen Z. Liu L, et al. Among authors: chen z. J Virol. 2007 May;81(9):4694-700. doi: 10.1128/JVI.02389-06. Epub 2007 Feb 21. J Virol. 2007. PMID: 17314167 Free PMC article.
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