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Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19.
Wong LR, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Pezzulo AA, Szachowicz PJ, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Meyerholz DK, Fortney K, McCray PB Jr, Perlman S. Wong LR, et al. bioRxiv [Preprint]. 2021 Apr 21:2021.04.20.440676. doi: 10.1101/2021.04.20.440676. bioRxiv. 2021. PMID: 33907749 Free PMC article. Preprint.
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike.
Tan TJC, Verma AK, Odle A, Lei R, Meyerholz DK, Matreyek KA, Perlman S, Wong LR, Wu NC. Tan TJC, et al. Among authors: wong lr. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2317222121. doi: 10.1073/pnas.2317222121. Epub 2024 Apr 1. Proc Natl Acad Sci U S A. 2024. PMID: 38557175 Free PMC article.
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning.
Lei R, Qing E, Odle A, Yuan M, Tan TJC, So N, Ouyang WO, Wilson IA, Gallagher T, Perlman S, Wu NC, Wong LR. Lei R, et al. Among authors: wong lr. bioRxiv [Preprint]. 2023 Nov 29:2023.11.28.569051. doi: 10.1101/2023.11.28.569051. bioRxiv. 2023. Update in: Nat Commun. 2024 May 14;15(1):4056. doi: 10.1038/s41467-024-48104-8. PMID: 38076875 Free PMC article. Updated. Preprint.
Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence.
Li P, Xue B, Schnicker NJ, Wong LR, Meyerholz DK, Perlman S. Li P, et al. Among authors: wong lr. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2305674120. doi: 10.1073/pnas.2305674120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487098 Free PMC article.
Omicron subvariant BA.5 efficiently infects lung cells.
Hoffmann M, Wong LR, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. Hoffmann M, et al. Among authors: wong lr. Nat Commun. 2023 Jun 13;14(1):3500. doi: 10.1038/s41467-023-39147-4. Nat Commun. 2023. PMID: 37311762 Free PMC article.
39 results