Bottini N - Search Results

1

Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase.

Stanford SM, Diaz MA, Ardecky RJ, Zou J, Roosild T, Holmes ZJ, Nguyen TP, Hedrick MP, Rodiles S, Guan A, Grotegut S, Santelli E, Chung TDY, Jackson MR, Bottini N, Pinkerton AB. Stanford SM, et al. Among authors: bottini n. J Med Chem. 2021 May 13;64(9):5645-5653. doi: 10.1021/acs.jmedchem.0c02126. Epub 2021 Apr 29. J Med Chem. 2021. PMID: 33914534 Free PMC article.

2

Protein tyrosine phosphatases.

Mustelin T, Feng GS, Bottini N, Alonso A, Kholod N, Birle D, Merlo J, Huynh H. Mustelin T, et al. Among authors: bottini n. Front Biosci. 2002 Jan 1;7:d85-142. doi: 10.2741/A770. Front Biosci. 2002. PMID: 11779706 Review.

3

Activation of ZAP-70 through specific dephosphorylation at the inhibitory Tyr-292 by the low molecular weight phosphotyrosine phosphatase (LMPTP).

Bottini N, Stefanini L, Williams S, Alonso A, Jascur T, Abraham RT, Couture C, Mustelin T. Bottini N, et al. J Biol Chem. 2002 Jul 5;277(27):24220-4. doi: 10.1074/jbc.M202885200. Epub 2002 Apr 25. J Biol Chem. 2002. PMID: 11976341 Free article.

4

Low-molecular-weight protein tyrosine phosphatase and human disease: in search of biochemical mechanisms.

Bottini N, Bottini E, Gloria-Bottini F, Mustelin T. Bottini N, et al. Among authors: bottini e. Arch Immunol Ther Exp (Warsz). 2002;50(2):95-104. Arch Immunol Ther Exp (Warsz). 2002. PMID: 12022706 Review.

5

Association of the acid phosphatase (ACP1) gene with triglyceride levels in obese women.

Bottini N, MacMurray J, Peters W, Rostamkhani M, Comings DE. Bottini N, et al. Mol Genet Metab. 2002 Nov;77(3):226-9. doi: 10.1016/s1096-7192(02)00120-8. Mol Genet Metab. 2002. PMID: 12409270

6

Convulsive disorder and the genetics of signal transduction; a study of a low molecular weight protein tyrosine phosphatase in a pediatric sample.

Bottini N, Saccucci P, Piciullo A, Iannetti P, Lucarini N, Lucarelli P, Gloria-Bottini F, Curatolo P. Bottini N, et al. Neurosci Lett. 2002 Nov 29;333(3):159-62. doi: 10.1016/s0304-3940(02)00758-9. Neurosci Lett. 2002. PMID: 12429372

7

Lck dephosphorylation at Tyr-394 and inhibition of T cell antigen receptor signaling by Yersinia phosphatase YopH.

Alonso A, Bottini N, Bruckner S, Rahmouni S, Williams S, Schoenberger SP, Mustelin T. Alonso A, et al. Among authors: bottini n. J Biol Chem. 2004 Feb 6;279(6):4922-8. doi: 10.1074/jbc.M308978200. Epub 2003 Nov 17. J Biol Chem. 2004. PMID: 14623872 Free article.

8

Protein tyrosine phosphatases in the human genome.

Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. Alonso A, et al. Among authors: bottini n. Cell. 2004 Jun 11;117(6):699-711. doi: 10.1016/j.cell.2004.05.018. Cell. 2004. PMID: 15186772 Free article. Review.

9

Inhibition of Yersinia tyrosine phosphatase by furanyl salicylate compounds.

Tautz L, Bruckner S, Sareth S, Alonso A, Bogetz J, Bottini N, Pellecchia M, Mustelin T. Tautz L, et al. Among authors: bottini n. J Biol Chem. 2005 Mar 11;280(10):9400-8. doi: 10.1074/jbc.M413122200. Epub 2004 Dec 22. J Biol Chem. 2005. PMID: 15615724 Free article.

10

Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study.

Krishnamurthy D, Karver MR, Fiorillo E, Orrú V, Stanford SM, Bottini N, Barrios AM. Krishnamurthy D, et al. Among authors: bottini n. J Med Chem. 2008 Aug 14;51(15):4790-5. doi: 10.1021/jm800101w. Epub 2008 Jul 8. J Med Chem. 2008. PMID: 18605719

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