Velazquez-Campoy A - Search Results

1

Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs.

Rizzuti B, Grande F, Conforti F, Jimenez-Alesanco A, Ceballos-Laita L, Ortega-Alarcon D, Vega S, Reyburn HT, Abian O, Velazquez-Campoy A. Rizzuti B, et al. Biomedicines. 2021 Apr 2;9(4):375. doi: 10.3390/biomedicines9040375. Biomedicines. 2021. PMID: 33918402 Free PMC article.

2

Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes.

Velazquez-Campoy A, Vega S, Freire E. Velazquez-Campoy A, et al. Biochemistry. 2002 Jul 9;41(27):8613-9. doi: 10.1021/bi020160i. Biochemistry. 2002. PMID: 12093278

3

Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design.

Velazquez-Campoy A, Muzammil S, Ohtaka H, Schön A, Vega S, Freire E. Velazquez-Campoy A, et al. Curr Drug Targets Infect Disord. 2003 Dec;3(4):311-28. doi: 10.2174/1568005033481051. Curr Drug Targets Infect Disord. 2003. PMID: 14754432 Review.

4

A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease.

Vega S, Kang LW, Velazquez-Campoy A, Kiso Y, Amzel LM, Freire E. Vega S, et al. Proteins. 2004 May 15;55(3):594-602. doi: 10.1002/prot.20069. Proteins. 2004. PMID: 15103623

5

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets.

Ohtaka H, Muzammil S, Schön A, Velazquez-Campoy A, Vega S, Freire E. Ohtaka H, et al. Int J Biochem Cell Biol. 2004 Sep;36(9):1787-99. doi: 10.1016/j.biocel.2004.02.021. Int J Biochem Cell Biol. 2004. PMID: 15183345 Review.

6

Thermodynamics of zinc binding to hepatitis C virus NS3 protease: a folding by binding event.

Abian O, Neira JL, Velazquez-Campoy A. Abian O, et al. Proteins. 2009 Nov 15;77(3):624-36. doi: 10.1002/prot.22475. Proteins. 2009. PMID: 19536779

7

Conformational stability of hepatitis C virus NS3 protease.

Abian O, Vega S, Neira JL, Velazquez-Campoy A. Abian O, et al. Biophys J. 2010 Dec 1;99(11):3811-20. doi: 10.1016/j.bpj.2010.10.037. Biophys J. 2010. PMID: 21112306 Free PMC article.

8

Protein-cation interactions: structural and thermodynamic aspects.

Arias-Moreno X, Abian O, Vega S, Sancho J, Velazquez-Campoy A. Arias-Moreno X, et al. Curr Protein Pept Sci. 2011 Jun;12(4):325-38. doi: 10.2174/138920311795906664. Curr Protein Pept Sci. 2011. PMID: 21401523 Review.

9

Mechanism of FMN Binding to the Apoflavodoxin from Helicobacter pylori.

Ayuso-Tejedor S, Abián O, Velázquez-Campoy A, Sancho J. Ayuso-Tejedor S, et al. Biochemistry. 2011 Oct 11;50(40):8703-11. doi: 10.1021/bi201025y. Epub 2011 Sep 15. Biochemistry. 2011. PMID: 21910456

10

Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase.

Abian O, Alfonso P, Velazquez-Campoy A, Giraldo P, Pocovi M, Sancho J. Abian O, et al. Mol Pharm. 2011 Dec 5;8(6):2390-7. doi: 10.1021/mp200313e. Epub 2011 Nov 3. Mol Pharm. 2011. PMID: 21988669

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