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Microglia in the Brain Tumor Microenvironment.
Cole AP, Hoffmeyer E, Chetty SL, Cruz-Cruz J, Hamrick F, Youssef O, Cheshier S, Mitra SS. Cole AP, et al. Among authors: mitra ss. Adv Exp Med Biol. 2020;1273:197-208. doi: 10.1007/978-3-030-49270-0_11. Adv Exp Med Biol. 2020. PMID: 33119883
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
Marquardt V, Theruvath J, Pauck D, Picard D, Qin N, Blümel L, Maue M, Bartl J, Ahmadov U, Langini M, Meyer FD, Cole A, Cruz-Cruz J, Graef CM, Wölfl M, Milde T, Witt O, Erdreich-Epstein A, Leprivier G, Kahlert U, Stefanski A, Stühler K, Keir ST, Bigner DD, Hauer J, Beez T, Knobbe-Thomsen CB, Fischer U, Felsberg J, Hansen FK, Vibhakar R, Venkatraman S, Cheshier SH, Reifenberger G, Borkhardt A, Kurz T, Remke M, Mitra S. Marquardt V, et al. J Immunother Cancer. 2023 Jan;11(1):e005871. doi: 10.1136/jitc-2022-005871. J Immunother Cancer. 2023. PMID: 36639156 Free PMC article.
Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma.
Hutter G, Theruvath J, Graef CM, Zhang M, Schoen MK, Manz EM, Bennett ML, Olson A, Azad TD, Sinha R, Chan C, Assad Kahn S, Gholamin S, Wilson C, Grant G, He J, Weissman IL, Mitra SS, Cheshier SH. Hutter G, et al. Among authors: mitra ss. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):997-1006. doi: 10.1073/pnas.1721434116. Epub 2019 Jan 2. Proc Natl Acad Sci U S A. 2019. PMID: 30602457 Free PMC article.
Glioblastoma stem cells and stem cell-targeting immunotherapies.
Esparza R, Azad TD, Feroze AH, Mitra SS, Cheshier SH. Esparza R, et al. Among authors: mitra ss. J Neurooncol. 2015 Jul;123(3):449-57. doi: 10.1007/s11060-015-1729-x. Epub 2015 Feb 15. J Neurooncol. 2015. PMID: 25682090 Review.
78 results