Ahsman MJ - Search Results

1

Understanding effect site pharmacology of uprifosbuvir, a hepatitis C virus nucleoside inhibitor: Case study of a multidisciplinary modeling approach in drug development.

van den Berg P, Gao W, Ahsman MJ, Arrington L, Kesisoglou F, Miller R, Post TM, Rizk ML. van den Berg P, et al. Among authors: ahsman mj. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):658-670. doi: 10.1002/psp4.12644. Epub 2021 Jun 18. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33934558 Free PMC article.

2

Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.

Willmann S, Ince I, Ahsman M, Coboeken K, Zhang Y, Thelen K, Kubitza D, Zannikos P, Zhou W, Pina LM, Post T, Lippert J. Willmann S, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Aug;11(8):1111-1121. doi: 10.1002/psp4.12830. Epub 2022 Jun 14. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35665486 Free PMC article.

3

Extending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APP.

van Maanen EMT, van Steeg TJ, Ahsman MJ, Michener MS, Savage MJ, Kennedy ME, Kleijn HJ, Stone J, Danhof M. van Maanen EMT, et al. Among authors: ahsman mj. J Pharmacol Exp Ther. 2018 Jun;365(3):507-518. doi: 10.1124/jpet.117.244699. Epub 2018 Mar 21. J Pharmacol Exp Ther. 2018. PMID: 29563326

4

A population K-PD model analysis of long-term testosterone inhibition in prostate cancer patients undergoing intermittent androgen deprivation therapy.

DeJongh J, Ahsman M, Snelder N. DeJongh J, et al. J Pharmacokinet Pharmacodyn. 2021 Aug;48(4):465-477. doi: 10.1007/s10928-020-09736-7. Epub 2021 Feb 4. J Pharmacokinet Pharmacodyn. 2021. PMID: 33538922 Clinical Trial.

5

Favorable Pharmacokinetic Characteristics of Extended-Half-Life Recombinant Factor VIII BAY 94-9027 Enable Robust Individual Profiling Using a Population Pharmacokinetic Approach.

Solms A, Iorio A, Ahsman MJ, Vis P, Shah A, Berntorp E, Garmann D. Solms A, et al. Among authors: ahsman mj. Clin Pharmacokinet. 2020 May;59(5):605-616. doi: 10.1007/s40262-019-00832-7. Clin Pharmacokinet. 2020. PMID: 31749076 Free PMC article.

6

Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration.

Kleiber N, Mathôt RAA, Ahsman MJ, Wildschut ED, Tibboel D, de Wildt SN. Kleiber N, et al. Among authors: ahsman mj. Br J Clin Pharmacol. 2017 Jun;83(6):1227-1239. doi: 10.1111/bcp.13235. Epub 2017 Feb 27. Br J Clin Pharmacol. 2017. PMID: 28078682 Free PMC article.

7

Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients.

Berends SE, van Steeg TJ, Ahsman MJ, Singh S, Brandse JF, D'Haens GRAM, Mathôt RAA. Berends SE, et al. Among authors: ahsman mj. J Pharmacokinet Pharmacodyn. 2019 Dec;46(6):543-551. doi: 10.1007/s10928-019-09652-5. Epub 2019 Sep 5. J Pharmacokinet Pharmacodyn. 2019. PMID: 31489538 Free PMC article.

8

Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A.

Solms A, Shah A, Berntorp E, Tiede A, Iorio A, Linardi C, Ahsman M, Mancuso ME, Zhivkov T, Lissitchkov T. Solms A, et al. Ann Hematol. 2020 Nov;99(11):2689-2698. doi: 10.1007/s00277-020-04280-3. Epub 2020 Sep 24. Ann Hematol. 2020. PMID: 32974838 Free PMC article. Clinical Trial.

9

Direct comparison of two extended-half-life recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A.

Shah A, Solms A, Wiegmann S, Ahsman M, Berntorp E, Tiede A, Iorio A, Mancuso ME, Zhivkov T, Lissitchkov T. Shah A, et al. Ann Hematol. 2019 Sep;98(9):2035-2044. doi: 10.1007/s00277-019-03747-2. Epub 2019 Jun 24. Ann Hematol. 2019. PMID: 31236667 Free PMC article. Clinical Trial.

10

Feasibility of sedation and analgesia interruption following cannulation in neonates on extracorporeal membrane oxygenation.

Wildschut ED, Hanekamp MN, Vet NJ, Houmes RJ, Ahsman MJ, Mathot RA, de Wildt SN, Tibboel D. Wildschut ED, et al. Among authors: ahsman mj. Intensive Care Med. 2010 Sep;36(9):1587-91. doi: 10.1007/s00134-010-1931-4. Epub 2010 May 28. Intensive Care Med. 2010. PMID: 20508914 Free PMC article.

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