Ohuchi M - Search Results

1

Visualization of Intratumor Pharmacokinetics of [fam-] Trastuzumab Deruxtecan (DS-8201a) in HER2 Heterogeneous Model Using Phosphor-integrated Dots Imaging Analysis.

Suzuki M, Yagishita S, Sugihara K, Ogitani Y, Nishikawa T, Ohuchi M, Teishikata T, Jikoh T, Yatabe Y, Yonemori K, Tamura K, Hasegawa K, Hamada A. Suzuki M, et al. Among authors: ohuchi m. Clin Cancer Res. 2021 Jul 15;27(14):3970-3979. doi: 10.1158/1078-0432.CCR-21-0397. Epub 2021 May 12. Clin Cancer Res. 2021. PMID: 33980613

2

High-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of raltegravir, dolutegravir and elvitegravir concentrations in human plasma and cerebrospinal fluid samples.

Tsuchiya K, Ohuchi M, Yamane N, Aikawa H, Gatanaga H, Oka S, Hamada A. Tsuchiya K, et al. Among authors: ohuchi m. Biomed Chromatogr. 2018 Feb;32(2). doi: 10.1002/bmc.4058. Epub 2017 Aug 21. Biomed Chromatogr. 2018. PMID: 28762239

3

Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging.

Tsubata Y, Hayashi M, Tanino R, Aikawa H, Ohuchi M, Tamura K, Fujiwara Y, Isobe T, Hamada A. Tsubata Y, et al. Among authors: ohuchi m. Sci Rep. 2017 Oct 3;7(1):12622. doi: 10.1038/s41598-017-13025-8. Sci Rep. 2017. PMID: 28974758 Free PMC article.

4

Visualization of the distribution of nanoparticle-formulated AZD2811 in mouse tumor model using matrix-assisted laser desorption ionization mass spectrometry imaging.

Ryu S, Ohuchi M, Yagishita S, Shimoi T, Yonemori K, Tamura K, Fujiwara Y, Hamada A. Ryu S, et al. Among authors: ohuchi m. Sci Rep. 2020 Sep 23;10(1):15535. doi: 10.1038/s41598-020-72665-5. Sci Rep. 2020. PMID: 32968211 Free PMC article.

5

Use of an alternative signature peptide during development of a LC-MS/MS assay of plasma nivolumab levels applicable for multiple species.

Ohuchi M, Yagishita S, Taguchi K, Goto Y, Fukahori M, Enoki Y, Shimada T, Yamaguchi M, Matsumoto K, Hamada A. Ohuchi M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 1;1162:122489. doi: 10.1016/j.jchromb.2020.122489. Epub 2020 Dec 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 33385769

6

A procedure for method development and protein binding ratio as the indicator of sensitivity with anticancer agents on MALDI mass spectrometry imaging.

Hayashi Y, Ohuchi M, Ryu S, Yagishita S, Hamada A. Hayashi Y, et al. Among authors: ohuchi m. Drug Metab Pharmacokinet. 2021 Jun;38:100385. doi: 10.1016/j.dmpk.2021.100385. Epub 2021 Jan 30. Drug Metab Pharmacokinet. 2021. PMID: 33878680 Free article.

7

Augmented Clearance of Nivolumab Is Associated with Renal Functions in Chronic Renal Disease Model Rats.

Taguchi K, Hayashi Y, Ohuchi M, Yamada H, Yagishita S, Enoki Y, Matsumoto K, Hamada A. Taguchi K, et al. Among authors: ohuchi m. Drug Metab Dispos. 2022 Jun;50(6):822-826. doi: 10.1124/dmd.121.000520. Epub 2021 Aug 4. Drug Metab Dispos. 2022. PMID: 34348939

8

The Long Half-Life of Programmed Cell Death Protein 1 Inhibitors May Increase the Frequency of Immune-Related Adverse Events After Subsequent EGFR Tyrosine Kinase Inhibitor Therapy.

Shinno Y, Goto Y, Ohuchi M, Hamada A, Nokihara H, Fujiwara Y, Ohe Y. Shinno Y, et al. Among authors: ohuchi m. JTO Clin Res Rep. 2020 Feb 11;1(1):100008. doi: 10.1016/j.jtocrr.2020.100008. eCollection 2020 Mar. JTO Clin Res Rep. 2020. PMID: 34589912 Free PMC article.

9

Safety Implications of Switching Pembrolizumab Dosage From 200 mg Every 3 Weeks to 400 mg Every 6 Weeks in Patients With Advanced NSCLC.

Higashiyama RI, Yoshida T, Yagishita S, Ohuchi M, Sakiyama N, Torasawa M, Shirasawa M, Masuda K, Shinno Y, Matsumoto Y, Okuma Y, Goto Y, Horinouchi H, Yamamoto N, Hamada A, Ohe Y. Higashiyama RI, et al. Among authors: ohuchi m. J Thorac Oncol. 2022 Oct;17(10):1227-1232. doi: 10.1016/j.jtho.2022.06.010. Epub 2022 Jul 3. J Thorac Oncol. 2022. PMID: 35788404 Free article.

10

Development of an analytical method to determine E7130 concentration in mouse plasma by micro-sampling using ultra-performance liquid chromatography-high resolution mass spectrometry.

Ryu S, Hayashi Y, Yagishita S, Takahashi A, Yokoi A, Ohuchi M, Hamada A. Ryu S, et al. Among authors: ohuchi m. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Sep 1;1207:123366. doi: 10.1016/j.jchromb.2022.123366. Epub 2022 Jul 14. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35853391

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