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Page 1
Augmentation of Stimulator of Interferon Genes-Induced Type I Interferon Production in COPA Syndrome.
Kato T, Yamamoto M, Honda Y, Orimo T, Sasaki I, Murakami K, Hemmi H, Fukuda-Ohta Y, Isono K, Takayama S, Nakamura H, Otsuki Y, Miyamoto T, Takita J, Yasumi T, Nishikomori R, Matsubayashi T, Izawa K, Kaisho T. Kato T, et al. Among authors: fukuda ohta y. Arthritis Rheumatol. 2021 Nov;73(11):2105-2115. doi: 10.1002/art.41790. Arthritis Rheumatol. 2021. PMID: 33982886
Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency.
Kanazawa N, Hemmi H, Kinjo N, Ohnishi H, Hamazaki J, Mishima H, Kinoshita A, Mizushima T, Hamada S, Hamada K, Kawamoto N, Kadowaki S, Honda Y, Izawa K, Nishikomori R, Tsumura M, Yamashita Y, Tamura S, Orimo T, Ozasa T, Kato T, Sasaki I, Fukuda-Ohta Y, Wakaki-Nishiyama N, Inaba Y, Kunimoto K, Okada S, Taketani T, Nakanishi K, Murata S, Yoshiura KI, Kaisho T. Kanazawa N, et al. Among authors: fukuda ohta y. Nat Commun. 2021 Nov 24;12(1):6819. doi: 10.1038/s41467-021-27085-y. Nat Commun. 2021. PMID: 34819510 Free PMC article.
The mechanism of action of Spi-B in the transcriptional activation of the interferon-α4 gene.
Miyazaki R, Saiga H, Kato T, Bakoshi T, Senba R, Shintani A, Suzuki M, Takao K, Sasaki I, Iizuka A, Sugiyama M, Iwami N, Fukuda-Ohta Y, Hemmi H, Tanaka T, Miyake M, Kaisho T, Hoshino K. Miyazaki R, et al. Among authors: fukuda ohta y. Biochem Biophys Res Commun. 2020 Apr 30;525(2):477-482. doi: 10.1016/j.bbrc.2020.02.101. Epub 2020 Feb 25. Biochem Biophys Res Commun. 2020. PMID: 32111355
Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis.
Sasaki I, Kato T, Hemmi H, Fukuda-Ohta Y, Wakaki-Nishiyama N, Yamamoto A, Kaisho T. Sasaki I, et al. Among authors: fukuda ohta y. Front Immunol. 2022 May 27;13:857954. doi: 10.3389/fimmu.2022.857954. eCollection 2022. Front Immunol. 2022. PMID: 35693801 Free PMC article. Review.
Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9-genome editing promotes antitumor immunity and suppresses ovarian cancer progression.
Yahata T, Mizoguchi M, Kimura A, Orimo T, Toujima S, Kuninaka Y, Nosaka M, Ishida Y, Sasaki I, Fukuda-Ohta Y, Hemmi H, Iwahashi N, Noguchi T, Kaisho T, Kondo T, Ino K. Yahata T, et al. Among authors: fukuda ohta y. Cancer Sci. 2019 Apr;110(4):1279-1292. doi: 10.1111/cas.13958. Epub 2019 Feb 27. Cancer Sci. 2019. PMID: 30702189 Free PMC article.
Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome.
Orimo T, Sasaki I, Hemmi H, Ozasa T, Fukuda-Ohta Y, Ohta T, Morinaka M, Kitauchi M, Yamaguchi T, Sato Y, Tanaka T, Hoshino K, Katayama KI, Fukuda S, Miyake K, Yamamoto M, Satoh T, Furukawa K, Kuroda E, Ishii KJ, Takeda K, Kaisho T. Orimo T, et al. Among authors: fukuda ohta y. Int Immunol. 2019 Sep 18;31(10):657-668. doi: 10.1093/intimm/dxz004. Int Immunol. 2019. PMID: 30689886 Free PMC article.
Anticancer effects of chemokine-directed antigen delivery to a cross-presenting dendritic cell subset with immune checkpoint blockade.
Mizumoto Y, Hemmi H, Katsuda M, Miyazawa M, Kitahata Y, Miyamoto A, Nakamori M, Ojima T, Matsuda K, Nakamura M, Hayata K, Fukuda-Ohta Y, Sugiyama M, Ohta T, Orimo T, Okura S, Sasaki I, Tamada K, Yamaue H, Kaisho T. Mizumoto Y, et al. Among authors: fukuda ohta y. Br J Cancer. 2020 Apr;122(8):1185-1193. doi: 10.1038/s41416-020-0757-2. Epub 2020 Feb 18. Br J Cancer. 2020. PMID: 32066911 Free PMC article.
A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages.
Sasaki I, Fukuda-Ohta Y, Nakai C, Wakaki-Nishiyama N, Okamoto C, Okuzaki D, Morita S, Kaji S, Furuta Y, Hemmi H, Kato T, Yamamoto A, Tosuji E, Saitoh SI, Tanaka T, Hoshino K, Fukuda S, Miyake K, Kuroda E, Ishii KJ, Iwawaki T, Furukawa K, Kaisho T. Sasaki I, et al. Among authors: fukuda ohta y. Cell Rep. 2024 Apr 23;43(4):113981. doi: 10.1016/j.celrep.2024.113981. Epub 2024 Mar 24. Cell Rep. 2024. PMID: 38520688 Free article.