Mankin AS - Search Results

1

Context-specific action of macrolide antibiotics on the eukaryotic ribosome.

Svetlov MS, Koller TO, Meydan S, Shankar V, Klepacki D, Polacek N, Guydosh NR, Vázquez-Laslop N, Wilson DN, Mankin AS. Svetlov MS, et al. Among authors: mankin as. Nat Commun. 2021 May 14;12(1):2803. doi: 10.1038/s41467-021-23068-1. Nat Commun. 2021. PMID: 33990576 Free PMC article.

2

A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit.

Belova L, Tenson T, Xiong L, McNicholas PM, Mankin AS. Belova L, et al. Among authors: mankin as. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3726-31. doi: 10.1073/pnas.071527498. Epub 2001 Mar 20. Proc Natl Acad Sci U S A. 2001. PMID: 11259679 Free PMC article.

3

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide.

Polacek N, Gaynor M, Yassin A, Mankin AS. Polacek N, et al. Among authors: mankin as. Nature. 2001 May 24;411(6836):498-501. doi: 10.1038/35078113. Nature. 2001. PMID: 11373685

4

[Ribosomal antibiotics].

Man'kin AS. Man'kin AS. Mol Biol (Mosk). 2001 Jul-Aug;35(4):597-609. Mol Biol (Mosk). 2001. PMID: 11524946 Review. Russian.

5

pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive.

Xiong L, Polacek N, Sander P, Böttger EC, Mankin A. Xiong L, et al. RNA. 2001 Oct;7(10):1365-9. RNA. 2001. PMID: 11680840 Free PMC article.

6

Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA.

Garza-Ramos G, Xiong L, Zhong P, Mankin A. Garza-Ramos G, et al. J Bacteriol. 2001 Dec;183(23):6898-907. doi: 10.1128/JB.183.23.6898-6907.2001. J Bacteriol. 2001. PMID: 11698379 Free PMC article.

7

SPARK--a novel method to monitor ribosomal peptidyl transferase activity.

Polacek N, Swaney S, Shinabarger D, Mankin AS. Polacek N, et al. Among authors: mankin as. Biochemistry. 2002 Oct 1;41(39):11602-10. doi: 10.1021/bi026040s. Biochemistry. 2002. PMID: 12269803

8

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

Polacek N, Gomez MJ, Ito K, Xiong L, Nakamura Y, Mankin A. Polacek N, et al. Mol Cell. 2003 Jan;11(1):103-12. doi: 10.1016/s1097-2765(02)00825-0. Mol Cell. 2003. PMID: 12535525 Free article.

9

Macrolide antibiotics: binding site, mechanism of action, resistance.

Gaynor M, Mankin AS. Gaynor M, et al. Among authors: mankin as. Curr Top Med Chem. 2003;3(9):949-61. doi: 10.2174/1568026033452159. Curr Top Med Chem. 2003. PMID: 12678831 Review.

10

Binding site of the bridged macrolides in the Escherichia coli ribosome.

Xiong L, Korkhin Y, Mankin AS. Xiong L, et al. Among authors: mankin as. Antimicrob Agents Chemother. 2005 Jan;49(1):281-8. doi: 10.1128/AAC.49.1.281-288.2005. Antimicrob Agents Chemother. 2005. PMID: 15616307 Free PMC article.

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