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Page 1
ZZ-dependent regulation of p62/SQSTM1 in autophagy.
Zhang Y, Mun SR, Linares JF, Ahn J, Towers CG, Ji CH, Fitzwalter BE, Holden MR, Mi W, Shi X, Moscat J, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG. Zhang Y, et al. Among authors: linares jf. Nat Commun. 2018 Oct 22;9(1):4373. doi: 10.1038/s41467-018-06878-8. Nat Commun. 2018. PMID: 30349045 Free PMC article.
p62 is a key regulator of nutrient sensing in the mTORC1 pathway.
Duran A, Amanchy R, Linares JF, Joshi J, Abu-Baker S, Porollo A, Hansen M, Moscat J, Diaz-Meco MT. Duran A, et al. Among authors: linares jf. Mol Cell. 2011 Oct 7;44(1):134-46. doi: 10.1016/j.molcel.2011.06.038. Mol Cell. 2011. PMID: 21981924 Free PMC article.
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.
Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, Yamaguchi K, Koike K, Itoh Y, Diaz-Meco MT, Moscat J, Karin M. Umemura A, et al. Among authors: linares jf. Cancer Cell. 2016 Jun 13;29(6):935-948. doi: 10.1016/j.ccell.2016.04.006. Epub 2016 May 19. Cancer Cell. 2016. PMID: 27211490 Free PMC article.
Mechanistic insight into the regulation of SQSTM1/p62.
Zhang Y, Mun SR, Linares JF, Towers CG, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG. Zhang Y, et al. Among authors: linares jf. Autophagy. 2019 Apr;15(4):735-737. doi: 10.1080/15548627.2019.1569935. Epub 2019 Jan 22. Autophagy. 2019. PMID: 30653391 Free PMC article.
PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.
Kudo Y, Sugimoto M, Arias E, Kasashima H, Cordes T, Linares JF, Duran A, Nakanishi Y, Nakanishi N, L'Hermitte A, Campos A, Senni N, Rooslid T, Roberts LR, Cuervo AM, Metallo CM, Karin M, Diaz-Meco MT, Moscat J. Kudo Y, et al. Among authors: linares jf. Cancer Cell. 2020 Aug 10;38(2):247-262.e11. doi: 10.1016/j.ccell.2020.05.018. Epub 2020 Jun 25. Cancer Cell. 2020. PMID: 32589943 Free PMC article.
Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population.
Kasashima H, Duran A, Martinez-Ordoñez A, Nakanishi Y, Kinoshita H, Linares JF, Reina-Campos M, Kudo Y, L'Hermitte A, Yashiro M, Ohira M, Bao F, Tauriello DVF, Batlle E, Diaz-Meco MT, Moscat J. Kasashima H, et al. Among authors: linares jf. Dev Cell. 2021 Jan 11;56(1):95-110.e10. doi: 10.1016/j.devcel.2020.10.014. Epub 2020 Nov 17. Dev Cell. 2021. PMID: 33207226 Free PMC article.
47 results