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RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness.
Benítez S, Cordero A, Santamaría PG, Redondo-Pedraza J, Rocha AS, Collado-Solé A, Jimenez M, Sanz-Moreno A, Yoldi G, Santos JC, De Benedictis I, Gómez-Aleza C, Da Silva-Álvarez S, Troulé K, Gómez-López G, Alcazar N, Palmero I, Collado M, Serrano M, Gonzalez-Suarez E. Benítez S, et al. Among authors: santamaria pg. Dev Cell. 2021 Jun 21;56(12):1727-1741.e7. doi: 10.1016/j.devcel.2021.04.022. Epub 2021 May 17. Dev Cell. 2021. PMID: 34004159 Free PMC article.
RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancer.
Sanz-Moreno A, Palomeras S, Pedersen K, Morancho B, Pascual T, Galván P, Benítez S, Gomez-Miragaya J, Ciscar M, Jimenez M, Pernas S, Petit A, Soler-Monsó MT, Viñas G, Alsaleem M, Rakha EA, Green AR, Santamaria PG, Mulder C, Lemeer S, Arribas J, Prat A, Puig T, Gonzalez-Suarez E. Sanz-Moreno A, et al. Among authors: santamaria pg. Breast Cancer Res. 2021 Mar 30;23(1):42. doi: 10.1186/s13058-021-01390-2. Breast Cancer Res. 2021. PMID: 33785053 Free PMC article.
E2A Modulates Stemness, Metastasis, and Therapeutic Resistance of Breast Cancer.
López-Menéndez C, Vázquez-Naharro A, Santos V, Dubus P, Santamaría PG, Martínez-Ramírez Á, Portillo F, Moreno-Bueno G, Faraldo MM, Cano A. López-Menéndez C, et al. Among authors: santamaria pg. Cancer Res. 2021 Sep 1;81(17):4529-4544. doi: 10.1158/0008-5472.CAN-20-2685. Epub 2021 Jun 18. Cancer Res. 2021. PMID: 34145034 Free PMC article.
Deconstructing ERK signaling in tumorigenesis.
Santamaria PG, Nebreda AR. Santamaria PG, et al. Mol Cell. 2010 Apr 9;38(1):3-5. doi: 10.1016/j.molcel.2010.03.012. Mol Cell. 2010. PMID: 20385084 Free article.
Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer.
Salvador F, Martin A, López-Menéndez C, Moreno-Bueno G, Santos V, Vázquez-Naharro A, Santamaria PG, Morales S, Dubus PR, Muinelo-Romay L, López-López R, Tung JC, Weaver VM, Portillo F, Cano A. Salvador F, et al. Among authors: santamaria pg. Cancer Res. 2017 Nov 1;77(21):5846-5859. doi: 10.1158/0008-5472.CAN-16-3152. Epub 2017 Jul 18. Cancer Res. 2017. PMID: 28720577 Free PMC article.
EMT: Present and future in clinical oncology.
Santamaria PG, Moreno-Bueno G, Portillo F, Cano A. Santamaria PG, et al. Mol Oncol. 2017 Jul;11(7):718-738. doi: 10.1002/1878-0261.12091. Epub 2017 Jun 27. Mol Oncol. 2017. PMID: 28590039 Free PMC article. Review.
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