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In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Diamond M, Chen R, Winkler E, Case J, Aziati I, Bricker T, Joshi A, Darling T, Ying B, Errico J, Shrihari S, VanBlargan L, Xie X, Gilchuk P, Zost S, Droit L, Liu Z, Stumpf S, Wang D, Handley S, Stine W, Shi PY, Garcia-Knight M, Andino R, Chiu C, Ellebedy A, Fremont D, Whelan S, Crowe J, Purcell L, Corti D, Boon A. Diamond M, et al. Among authors: handley s. Res Sq [Preprint]. 2021 Apr 23:rs.3.rs-448370. doi: 10.21203/rs.3.rs-448370/v1. Res Sq. 2021. Update in: Nature. 2021 Aug;596(7870):103-108. doi: 10.1038/s41586-021-03720-y PMID: 34013259 Free PMC article. Updated. Preprint.
A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope.
VanBlargan L, Adams L, Liu Z, Chen RE, Gilchuk P, Raju S, Smith B, Zhao H, Case JB, Winkler ES, Whitener B, Droit L, Aziati I, Shi PY, Creanga A, Pegu A, Handley S, Wang D, Boon A, Crowe JE, Whelan SPJ, Fremont D, Diamond M. VanBlargan L, et al. Among authors: handley s. bioRxiv [Preprint]. 2021 Apr 26:2021.04.26.441501. doi: 10.1101/2021.04.26.441501. bioRxiv. 2021. Update in: Immunity. 2021 Oct 12;54(10):2399-2416.e6. doi: 10.1016/j.immuni.2021.08.016 PMID: 33907753 Free PMC article. Updated. Preprint.
The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2.
Janowski AB, Jiang H, Fujii C, Owen MC, Bricker TL, Darling TL, Harastani HH, Seehra K, Tahan S, Jung A, Febles B, Blatter JA, Handley SA, Parikh BA, Lulla V, Boon AC, Wang D. Janowski AB, et al. Among authors: handley sa. bioRxiv [Preprint]. 2022 May 2:2022.04.30.486882. doi: 10.1101/2022.04.30.486882. bioRxiv. 2022. Update in: J Virol. 2023 Jun 29;97(6):e0063523. doi: 10.1128/jvi.00635-23 PMID: 35547847 Free PMC article. Updated. Preprint.
The highly conserved stem-loop II motif is dispensable for SARS-CoV-2.
Jiang H, Joshi A, Gan T, Janowski AB, Fujii C, Bricker TL, Darling TL, Harastani HH, Seehra K, Chen H, Tahan S, Jung A, Febles B, Blatter JA, Handley SA, Parikh BA, Wang D, Boon AC. Jiang H, et al. Among authors: handley sa. bioRxiv [Preprint]. 2023 Mar 16:2023.03.15.532878. doi: 10.1101/2023.03.15.532878. bioRxiv. 2023. Update in: J Virol. 2023 Jun 29;97(6):e0063523. doi: 10.1128/jvi.00635-23 PMID: 36993345 Free PMC article. Updated. Preprint.
Dengue Virus Surveillance in Nepal Yields the First On-Site Whole Genome Sequences of Isolates from the 2022 Outbreak.
Napit R, Ngono AE, Mihindukulasuriya KA, Pradhan A, Khadka B, Shrestha S, Droit L, Paredes A, Karki L, Khatiwada R, Tamang M, Chalise BS, Rawal M, Jha B, Wang D, Handley SA, Shresta S, Manandhar KD. Napit R, et al. Among authors: handley sa. bioRxiv [Preprint]. 2024 Jun 3:2024.06.02.597008. doi: 10.1101/2024.06.02.597008. bioRxiv. 2024. Update in: BMC Genomics. 2024 Oct 24;25(1):998. doi: 10.1186/s12864-024-10879-x PMID: 38895410 Free PMC article. Updated. Preprint.
Extracorporeal Life Support: Making Ethically Sound Allocation Decisions for a Limited Resource.
Lewis-Newby M, Wightman AG, Banker KA, Dudzinski DM, Handley SJ, Mazor RL, McGuire JK, McMullan DM, Rice-Townsend SE, Soh E, Yalon L, Diekema DS, Berkman ER. Lewis-Newby M, et al. Among authors: handley sj. Pediatr Crit Care Med. 2024 Dec 1;25(12):e449-e458. doi: 10.1097/PCC.0000000000003608. Epub 2024 Sep 18. Pediatr Crit Care Med. 2024. PMID: 39630074 No abstract available.
Genomic surveillance of SARS-CoV-2 in Nepal.
Khadka B, Napit R, Mihindukulasuriya KA, Shrestha S, Rauniyar R, Tuladhar ET, Droit L, Paredes AM, Jha R, Raut R, Jha BK, Handley SA, Elong-Ngono A, Shresta S, Wang D, Manandhar KD. Khadka B, et al. Among authors: handley sa. Microbiol Resour Announc. 2024 Dec 12;13(12):e0078924. doi: 10.1128/mra.00789-24. Epub 2024 Nov 12. Microbiol Resour Announc. 2024. PMID: 39530702 Free PMC article.
372 results