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Preclinical trial of a MAP4K4 inhibitor to reduce infarct size in the pig: does cardioprotection in human stem cell-derived myocytes predict success in large mammals?
Te Lintel Hekkert M, Newton G, Chapman K, Aqil R, Downham R, Yan R, Merkus D, Whitlock G, Lane CAL, Cawkill D, Perrior T, Duncker DJ, Schneider MD. Te Lintel Hekkert M, et al. Basic Res Cardiol. 2021 May 20;116(1):34. doi: 10.1007/s00395-021-00875-7. Basic Res Cardiol. 2021. PMID: 34018053 Free PMC article.
Myocardium tolerant to an adenosine-dependent ischemic preconditioning stimulus can still be protected by stimuli that employ alternative signaling pathways.
Liem DA, te Lintel Hekkert M, Manintveld OC, Boomsma F, Verdouw PD, Duncker DJ. Liem DA, et al. Among authors: te lintel hekkert m. Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1165-72. doi: 10.1152/ajpheart.00899.2004. Epub 2004 Oct 14. Am J Physiol Heart Circ Physiol. 2005. PMID: 15486028 Free article.
Cardiac effects of postconditioning depend critically on the duration of index ischemia.
Manintveld OC, Te Lintel Hekkert M, van den Bos EJ, Suurenbroek GM, Dekkers DH, Verdouw PD, Lamers JM, Duncker DJ. Manintveld OC, et al. Among authors: te lintel hekkert m. Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1551-60. doi: 10.1152/ajpheart.00151.2006. Epub 2006 Nov 22. Am J Physiol Heart Circ Physiol. 2007. PMID: 17122197 Free article.
Coronary-aortic interaction during ventricular isovolumic contraction.
van Houwelingen MJ, Merkus D, Te Lintel Hekkert M, van Dijk G, Hoeks AP, Duncker DJ. van Houwelingen MJ, et al. Among authors: te lintel hekkert m. Med Biol Eng Comput. 2011 Aug;49(8):917-24. doi: 10.1007/s11517-011-0770-y. Epub 2011 Apr 13. Med Biol Eng Comput. 2011. PMID: 21487819 Free PMC article.
A novel approach to assess hemorrhagic shock severity using the arterially determined left ventricular isovolumic contraction period.
van Houwelingen MJ, Merkus D, Hofland J, Bakker J, Tenbrinck R, Te Lintel Hekkert M, van Dijk G, Hoeks AP, Duncker DJ. van Houwelingen MJ, et al. Among authors: te lintel hekkert m. Am J Physiol Heart Circ Physiol. 2013 Dec;305(12):H1790-7. doi: 10.1152/ajpheart.00504.2013. Epub 2013 Oct 11. Am J Physiol Heart Circ Physiol. 2013. PMID: 24124184 Free article.
Vagal nerve stimulation started just prior to reperfusion limits infarct size and no-reflow.
Uitterdijk A, Yetgin T, te Lintel Hekkert M, Sneep S, Krabbendam-Peters I, van Beusekom HM, Fischer TM, Cornelussen RN, Manintveld OC, Merkus D, Duncker DJ. Uitterdijk A, et al. Among authors: te lintel hekkert m. Basic Res Cardiol. 2015 Sep;110(5):508. doi: 10.1007/s00395-015-0508-3. Epub 2015 Aug 26. Basic Res Cardiol. 2015. PMID: 26306761 Free PMC article.
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