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Enhancer release and retargeting activates disease-susceptibility genes.
Oh S, Shao J, Mitra J, Xiong F, D'Antonio M, Wang R, Garcia-Bassets I, Ma Q, Zhu X, Lee JH, Nair SJ, Yang F, Ohgi K, Frazer KA, Zhang ZD, Li W, Rosenfeld MG. Oh S, et al. Among authors: lee jh. Nature. 2021 Jul;595(7869):735-740. doi: 10.1038/s41586-021-03577-1. Epub 2021 May 26. Nature. 2021. PMID: 34040254 Free PMC article.
The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis.
Nguyen TM, Kabotyanski EB, Reineke LC, Shao J, Xiong F, Lee JH, Dubrulle J, Johnson H, Stossi F, Tsoi PS, Choi KJ, Ellis AG, Zhao N, Cao J, Adewunmi O, Ferreon JC, Ferreon ACM, Neilson JR, Mancini MA, Chen X, Kim J, Ma L, Li W, Rosen JM. Nguyen TM, et al. Among authors: lee jh. Nucleic Acids Res. 2020 Mar 18;48(5):2621-2642. doi: 10.1093/nar/gkz1176. Nucleic Acids Res. 2020. PMID: 31863590 Free PMC article.
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation.
Lee JH, Wang R, Xiong F, Krakowiak J, Liao Z, Nguyen PT, Moroz-Omori EV, Shao J, Zhu X, Bolt MJ, Wu H, Singh PK, Bi M, Shi CJ, Jamal N, Li G, Mistry R, Jung SY, Tsai KL, Ferreon JC, Stossi F, Caflisch A, Liu Z, Mancini MA, Li W. Lee JH, et al. Mol Cell. 2021 Aug 19;81(16):3368-3385.e9. doi: 10.1016/j.molcel.2021.07.024. Epub 2021 Aug 9. Mol Cell. 2021. PMID: 34375583 Free PMC article.
SARS-CoV-2 restructures host chromatin architecture.
Wang R, Lee JH, Kim J, Xiong F, Hasani LA, Shi Y, Simpson EN, Zhu X, Chen YT, Shivshankar P, Krakowiak J, Wang Y, Gilbert DM, Yuan X, Eltzschig HK, Li W. Wang R, et al. Among authors: lee jh. Nat Microbiol. 2023 Apr;8(4):679-694. doi: 10.1038/s41564-023-01344-8. Epub 2023 Mar 23. Nat Microbiol. 2023. PMID: 36959507 Free PMC article.
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