Knapp S - Search Results

1

C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.

Krishnathas GM, Strödke B, Mittmann L, Zech T, Berger LM, Reichel CA, Rösser S, Schmid T, Knapp S, Müller S, Bracher F, Fürst R, Bischoff-Kont I. Krishnathas GM, et al. Among authors: knapp s. FASEB J. 2021 Jun;35(6):e21656. doi: 10.1096/fj.202100037R. FASEB J. 2021. PMID: 34042211

2

Out of the box binding determines specificity of SH2 domain interaction.

Müller S, Knapp S. Müller S, et al. Among authors: knapp s. Structure. 2009 Aug 12;17(8):1040-1. doi: 10.1016/j.str.2009.07.002. Structure. 2009. PMID: 19679083 Free PMC article.

3

Bromodomains as therapeutic targets.

Muller S, Filippakopoulos P, Knapp S. Muller S, et al. Among authors: knapp s. Expert Rev Mol Med. 2011 Sep 13;13:e29. doi: 10.1017/S1462399411001992. Expert Rev Mol Med. 2011. PMID: 21933453 Free PMC article. Review.

4

7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.

Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F. Huber K, et al. Among authors: knapp s. J Med Chem. 2012 Jan 12;55(1):403-13. doi: 10.1021/jm201286z. Epub 2012 Jan 3. J Med Chem. 2012. PMID: 22136433 Free PMC article.

5

Targeting kinases for the treatment of inflammatory diseases.

Müller S, Knapp S. Müller S, et al. Among authors: knapp s. Expert Opin Drug Discov. 2010 Sep;5(9):867-81. doi: 10.1517/17460441.2010.504203. Epub 2010 Jul 15. Expert Opin Drug Discov. 2010. PMID: 22823261

6

Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.

Bennett J, Fedorov O, Tallant C, Monteiro O, Meier J, Gamble V, Savitsky P, Nunez-Alonso GA, Haendler B, Rogers C, Brennan PE, Müller S, Knapp S. Bennett J, et al. Among authors: knapp s. J Med Chem. 2016 Feb 25;59(4):1642-7. doi: 10.1021/acs.jmedchem.5b00458. Epub 2015 May 20. J Med Chem. 2016. PMID: 25974391 Free PMC article.

7

The ins and outs of selective kinase inhibitor development.

Müller S, Chaikuad A, Gray NS, Knapp S. Müller S, et al. Among authors: knapp s. Nat Chem Biol. 2015 Nov;11(11):818-21. doi: 10.1038/nchembio.1938. Nat Chem Biol. 2015. PMID: 26485069 No abstract available.

8

Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.

Chaikuad A, Lang S, Brennan PE, Temperini C, Fedorov O, Hollander J, Nachane R, Abell C, Müller S, Siegal G, Knapp S. Chaikuad A, et al. Among authors: knapp s. J Med Chem. 2016 Feb 25;59(4):1648-53. doi: 10.1021/acs.jmedchem.5b01719. Epub 2016 Jan 13. J Med Chem. 2016. PMID: 26731131 Free PMC article.

9

Epigenomic regulation of oncogenesis by chromatin remodeling.

Kumar R, Li DQ, Müller S, Knapp S. Kumar R, et al. Among authors: knapp s. Oncogene. 2016 Aug 25;35(34):4423-36. doi: 10.1038/onc.2015.513. Epub 2016 Jan 25. Oncogene. 2016. PMID: 26804164 Review.

10

Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.

Sdelci S, Lardeau CH, Tallant C, Klepsch F, Klaiber B, Bennett J, Rathert P, Schuster M, Penz T, Fedorov O, Superti-Furga G, Bock C, Zuber J, Huber KV, Knapp S, Müller S, Kubicek S. Sdelci S, et al. Among authors: knapp s. Nat Chem Biol. 2016 Jul;12(7):504-10. doi: 10.1038/nchembio.2080. Epub 2016 May 9. Nat Chem Biol. 2016. PMID: 27159579

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