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Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning.
Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y. Xiang X, et al. Among authors: church gm. Nat Commun. 2021 May 28;12(1):3238. doi: 10.1038/s41467-021-23576-0. Nat Commun. 2021. PMID: 34050182 Free PMC article.
Heritable genome editing in C. elegans via a CRISPR-Cas9 system.
Friedland AE, Tzur YB, Esvelt KM, Colaiácovo MP, Church GM, Calarco JA. Friedland AE, et al. Among authors: church gm. Nat Methods. 2013 Aug;10(8):741-3. doi: 10.1038/nmeth.2532. Epub 2013 Jun 30. Nat Methods. 2013. PMID: 23817069 Free PMC article.
Cas9 as a versatile tool for engineering biology.
Mali P, Esvelt KM, Church GM. Mali P, et al. Among authors: church gm. Nat Methods. 2013 Oct;10(10):957-63. doi: 10.1038/nmeth.2649. Nat Methods. 2013. PMID: 24076990 Free PMC article. Review.
CRISPR/Cas9-Directed Genome Editing of Cultured Cells.
Yang L, Yang JL, Byrne S, Pan J, Church GM. Yang L, et al. Among authors: church gm. Curr Protoc Mol Biol. 2014 Jul 1;107:31.1.1-31.1.17. doi: 10.1002/0471142727.mb3101s107. Curr Protoc Mol Biol. 2014. PMID: 24984853 Review.
Accurate whole genome sequencing as the ultimate genetic test.
Drmanac R, Peters BA, Church GM, Reid CA, Xu X. Drmanac R, et al. Among authors: church gm. Clin Chem. 2015 Jan;61(1):305-6. doi: 10.1373/clinchem.2014.224907. Epub 2014 Dec 5. Clin Chem. 2015. PMID: 25479756 No abstract available.
Highly efficient Cas9-mediated transcriptional programming.
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM. Chavez A, et al. Among authors: church gm. Nat Methods. 2015 Apr;12(4):326-8. doi: 10.1038/nmeth.3312. Epub 2015 Mar 2. Nat Methods. 2015. PMID: 25730490 Free PMC article.
622 results