Schaeffeler E - Search Results

1

Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.

Fendt R, Hofmann U, Schneider ARP, Schaeffeler E, Burghaus R, Yilmaz A, Blank LM, Kerb R, Lippert J, Schlender JF, Schwab M, Kuepfer L. Fendt R, et al. Among authors: schaeffeler e. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):782-793. doi: 10.1002/psp4.12646. Epub 2021 Jun 26. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34053199 Free PMC article. Clinical Trial.

2

High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC.

Schaeffeler E, Lang T, Zanger UM, Eichelbaum M, Schwab M. Schaeffeler E, et al. Clin Chem. 2001 Mar;47(3):548-55. Clin Chem. 2001. PMID: 11238310

3

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Drescher S, Schaeffeler E, Hitzl M, Hofmann U, Schwab M, Brinkmann U, Eichelbaum M, Fromm MF. Drescher S, et al. Among authors: schaeffeler e. Br J Clin Pharmacol. 2002 May;53(5):526-34. doi: 10.1046/j.1365-2125.2002.01591.x. Br J Clin Pharmacol. 2002. PMID: 11994059 Free PMC article. Clinical Trial.

4

Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease.

Furuno T, Landi MT, Ceroni M, Caporaso N, Bernucci I, Nappi G, Martignoni E, Schaeffeler E, Eichelbaum M, Schwab M, Zanger UM. Furuno T, et al. Among authors: schaeffeler e. Pharmacogenetics. 2002 Oct;12(7):529-34. doi: 10.1097/00008571-200210000-00004. Pharmacogenetics. 2002. PMID: 12360103

5

Pharmacokinetic modelling of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid of neurosurgical patients after short-term infusion of morphine.

Meineke I, Freudenthaler S, Hofmann U, Schaeffeler E, Mikus G, Schwab M, Prange HW, Gleiter CH, Brockmöller J. Meineke I, et al. Among authors: schaeffeler e. Br J Clin Pharmacol. 2002 Dec;54(6):592-603. doi: 10.1046/j.1365-2125.2002.t01-1-01689.x. Br J Clin Pharmacol. 2002. PMID: 12492606 Free article.

6

[Therapy of chronic inflammatory bowel diseases with azathioprine, 6-mercaptopurine and 6-thioguanine. Clinico-pharmacologic aspects].

Schwab M, Herrlinger K, Schaeffeler E, Stange EF. Schwab M, et al. Among authors: schaeffeler e. Dtsch Med Wochenschr. 2003 Feb 21;128(8):378-85. doi: 10.1055/s-2003-37378. Dtsch Med Wochenschr. 2003. PMID: 12594624 Review. German. No abstract available.

7

Digoxin pharmacokinetics and MDR1 genetic polymorphisms.

Verstuyft C, Schwab M, Schaeffeler E, Kerb R, Brinkmann U, Jaillon P, Funck-Brentano C, Becquemont L. Verstuyft C, et al. Among authors: schaeffeler e. Eur J Clin Pharmacol. 2003 Apr;58(12):809-12. doi: 10.1007/s00228-003-0567-5. Epub 2003 Mar 1. Eur J Clin Pharmacol. 2003. PMID: 12698307

8

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

Schaeffeler E, Schwab M, Eichelbaum M, Zanger UM. Schaeffeler E, et al. Hum Mutat. 2003 Dec;22(6):476-85. doi: 10.1002/humu.10280. Hum Mutat. 2003. PMID: 14635107

9

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

Hitzl M, Schaeffeler E, Hocher B, Slowinski T, Halle H, Eichelbaum M, Kaufmann P, Fritz P, Fromm MF, Schwab M. Hitzl M, et al. Among authors: schaeffeler e. Pharmacogenetics. 2004 May;14(5):309-18. doi: 10.1097/00008571-200405000-00006. Pharmacogenetics. 2004. PMID: 15115917

10

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants.

Schaeffeler E, Fischer C, Brockmeier D, Wernet D, Moerike K, Eichelbaum M, Zanger UM, Schwab M. Schaeffeler E, et al. Pharmacogenetics. 2004 Jul;14(7):407-17. doi: 10.1097/01.fpc.0000114745.08559.db. Pharmacogenetics. 2004. PMID: 15226673

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