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Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseases.
Lemurell M, Ulander J, Winiwarter S, Dahlén A, Davidsson Ö, Emtenäs H, Broddefalk J, Swanson M, Hovdal D, Plowright AT, Pettersen A, Rydén-Landergren M, Barlind J, Llinas A, Herslöf M, Drmota T, Sigfridsson K, Moses S, Whatling C. Lemurell M, et al. Among authors: dahlen a. J Med Chem. 2015 Jan 22;58(2):897-911. doi: 10.1021/jm501531v. Epub 2014 Dec 22. J Med Chem. 2015. PMID: 25478788
Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue.
Bood M, Füchtbauer AF, Wranne MS, Ro JJ, Sarangamath S, El-Sagheer AH, Rupert DLM, Fisher RS, Magennis SW, Jones AC, Höök F, Brown T, Kim BH, Dahlén A, Wilhelmsson LM, Grøtli M. Bood M, et al. Among authors: dahlen a. Chem Sci. 2018 Mar 1;9(14):3494-3502. doi: 10.1039/c7sc05448c. eCollection 2018 Apr 14. Chem Sci. 2018. PMID: 29780479 Free PMC article.
Interbase FRET in RNA: from A to Z.
Füchtbauer AF, Wranne MS, Bood M, Weis E, Pfeiffer P, Nilsson JR, Dahlén A, Grøtli M, Wilhelmsson LM. Füchtbauer AF, et al. Among authors: dahlen a. Nucleic Acids Res. 2019 Nov 4;47(19):9990-9997. doi: 10.1093/nar/gkz812. Nucleic Acids Res. 2019. PMID: 31544922 Free PMC article.
Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor.
Wypijewska Del Nogal A, Füchtbauer AF, Bood M, Nilsson JR, Wranne MS, Sarangamath S, Pfeiffer P, Rajan VS, El-Sagheer AH, Dahlén A, Brown T, Grøtli M, Wilhelmsson LM. Wypijewska Del Nogal A, et al. Among authors: dahlen a. Nucleic Acids Res. 2020 Aug 20;48(14):7640-7652. doi: 10.1093/nar/gkaa525. Nucleic Acids Res. 2020. PMID: 32558908 Free PMC article.
Stealth Fluorescence Labeling for Live Microscopy Imaging of mRNA Delivery.
Baladi T, Nilsson JR, Gallud A, Celauro E, Gasse C, Levi-Acobas F, Sarac I, Hollenstein MR, Dahlén A, Esbjörner EK, Wilhelmsson LM. Baladi T, et al. Among authors: dahlen a. J Am Chem Soc. 2021 Apr 14;143(14):5413-5424. doi: 10.1021/jacs.1c00014. Epub 2021 Apr 2. J Am Chem Soc. 2021. PMID: 33797236 Free PMC article.
Interbase-FRET binding assay for pre-microRNAs.
Bood M, Del Nogal AW, Nilsson JR, Edfeldt F, Dahlén A, Lemurell M, Wilhelmsson LM, Grøtli M. Bood M, et al. Among authors: dahlen a. Sci Rep. 2021 Apr 30;11(1):9396. doi: 10.1038/s41598-021-88922-0. Sci Rep. 2021. PMID: 33931703 Free PMC article.
97 results