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The expression of the immune checkpoint regulator VISTA correlates with improved overall survival in pT1/2 tumor stages in esophageal adenocarcinoma.
Loeser H, Kraemer M, Gebauer F, Bruns C, Schröder W, Zander T, Persa OD, Alakus H, Hoelscher A, Buettner R, Lohneis P, Quaas A. Loeser H, et al. Among authors: lohneis p. Oncoimmunology. 2019 Feb 27;8(5):e1581546. doi: 10.1080/2162402X.2019.1581546. eCollection 2019. Oncoimmunology. 2019. PMID: 31069143 Free PMC article.
Lymphocyte activation gene-3 (LAG3) mRNA and protein expression on tumour infiltrating lymphocytes (TILs) in oesophageal adenocarcinoma.
Gebauer F, Krämer M, Bruns C, Schlößer HA, Thelen M, Lohneis P, Schröder W, Zander T, Alakus H, Buettner R, Loeser H, Quaas A. Gebauer F, et al. Among authors: lohneis p. J Cancer Res Clin Oncol. 2020 Sep;146(9):2319-2327. doi: 10.1007/s00432-020-03295-7. Epub 2020 Jun 26. J Cancer Res Clin Oncol. 2020. PMID: 32592066 Free PMC article.
Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy.
Thelen M, Wennhold K, Lehmann J, Garcia-Marquez M, Klein S, Kochen E, Lohneis P, Lechner A, Wagener-Ryczek S, Plum PS, Velazquez Camacho O, Pfister D, Dörr F, Heldwein M, Hekmat K, Beutner D, Klussmann JP, Thangarajah F, Ratiu D, Malter W, Merkelbach-Bruse S, Bruns CJ, Quaas A, von Bergwelt-Baildon M, Schlößer HA. Thelen M, et al. Among authors: lohneis p. NPJ Precis Oncol. 2021 Jun 16;5(1):52. doi: 10.1038/s41698-021-00196-x. NPJ Precis Oncol. 2021. PMID: 34135436 Free PMC article.
Tertiary lymphoid structures in pancreatic cancer are structurally homologous, share gene expression patterns and B-cell clones with secondary lymphoid organs but show increased T-cell activation.
Lehmann J, Thelen M, Kreer C, Schran S, García-Marquez MA, Cisic I, Siepmann K, Hagen EM, Eckel HNC, Lohneis P, Kruger S, Boeck S, Ormanns S, Rudelius M, Werner J, Popp F, Klein F, von Bergwelt-Baildon MS, Bruns CJ, Quaas A, Wennhold K, Schlößer HA. Lehmann J, et al. Among authors: lohneis p. Cancer Immunol Res. 2024 Dec 11. doi: 10.1158/2326-6066.CIR-24-0299. Online ahead of print. Cancer Immunol Res. 2024. PMID: 39661055
70 results