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Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?
Marty S, Beekhuijzen M, Charlton A, Hallmark N, Hannas BR, Jacobi S, Melching-Kollmuss S, Sauer UG, Sheets LP, Strauss V, Urbisch D, Botham PA, van Ravenzwaay B. Marty S, et al. Among authors: hallmark n. Crit Rev Toxicol. 2021 Apr;51(4):328-358. doi: 10.1080/10408444.2021.1910625. Epub 2021 Jun 2. Crit Rev Toxicol. 2021. PMID: 34074207 Review.
Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part I: which parameters from human studies are most relevant for toxicological assessments?
Sauer UG, Asiimwe A, Botham PA, Charlton A, Hallmark N, Jacobi S, Marty S, Melching-Kollmuss S, Palha JA, Strauss V, van Ravenzwaay B, Swaen G. Sauer UG, et al. Among authors: hallmark n. Crit Rev Toxicol. 2020 Oct;50(9):740-763. doi: 10.1080/10408444.2020.1839380. Epub 2020 Dec 11. Crit Rev Toxicol. 2020. PMID: 33305658 Review.
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny-part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?
Marty MS, Sauer UG, Charlton A, Ghaffari R, Guignard D, Hallmark N, Hannas BR, Jacobi S, Marxfeld HA, Melching-Kollmuss S, Sheets LP, Urbisch D, Botham PA, van Ravenzwaay B. Marty MS, et al. Among authors: hallmark n. Crit Rev Toxicol. 2022 Aug;52(7):546-617. doi: 10.1080/10408444.2022.2130166. Epub 2022 Dec 15. Crit Rev Toxicol. 2022. PMID: 36519295 Review.
A modular approach to the extended one-generation reproduction toxicity study. The outcome of an ECETOC Task Force and International ECETOC/ECVAM Workshop.
Moore N, Bremer S, Carmichael N, Daston G, Dent M, Gaoua-Chapelle W, Hallmark N, Hartung T, Holzum B, Hübel U, Meisters ML, Schneider S, van Ravenzwaay B, Hennes C. Moore N, et al. Among authors: hallmark n. Altern Lab Anim. 2009 Apr;37(2):219-25. doi: 10.1177/026119290903700211. Altern Lab Anim. 2009. PMID: 19453218 No abstract available.
Science based guidance for the assessment of endocrine disrupting properties of chemicals.
Bars R, Broeckaert F, Fegert I, Gross M, Hallmark N, Kedwards T, Lewis D, O'Hagan S, Panter GH, Weltje L, Weyers A, Wheeler JR, Galay-Burgos M. Bars R, et al. Among authors: hallmark n. Regul Toxicol Pharmacol. 2011 Feb;59(1):37-46. doi: 10.1016/j.yrtph.2010.09.003. Epub 2010 Sep 19. Regul Toxicol Pharmacol. 2011. PMID: 20858523
Guidance on classification for reproductive toxicity under the globally harmonized system of classification and labelling of chemicals (GHS).
Moore NP, Boogaard PJ, Bremer S, Buesen R, Edwards J, Fraysse B, Hallmark N, Hemming H, Langrand-Lerche C, McKee RH, Meisters ML, Parsons P, Politano V, Reader S, Ridgway P, Hennes C. Moore NP, et al. Among authors: hallmark n. Crit Rev Toxicol. 2013 Nov;43(10):850-91. doi: 10.3109/10408444.2013.854734. Crit Rev Toxicol. 2013. PMID: 24274377 Review.
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