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Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Rongvaux A, et al. Among authors: li t. Cell. 2014 Dec 18;159(7):1563-77. doi: 10.1016/j.cell.2014.11.037. Cell. 2014. PMID: 25525875 Free PMC article.
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Gao D, Li T, Li XD, Chen X, Li QZ, Wight-Carter M, Chen ZJ. Gao D, et al. Among authors: li t, li xd, li qz. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5699-705. doi: 10.1073/pnas.1516465112. Epub 2015 Sep 14. Proc Natl Acad Sci U S A. 2015. PMID: 26371324 Free PMC article.
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing.
Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. Golden RJ, et al. Among authors: li t. Nature. 2017 Feb 9;542(7640):197-202. doi: 10.1038/nature21025. Epub 2017 Jan 23. Nature. 2017. PMID: 28114302 Free PMC article.
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