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Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
Bailus BJ, Scheeler SM, Simons J, Sanchez MA, Tshilenge KT, Creus-Muncunill J, Naphade S, Lopez-Ramirez A, Zhang N, Lakshika Madushani K, Moroz S, Loureiro A, Schreiber KH, Hausch F, Kennedy BK, Ehrlich ME, Ellerby LM. Bailus BJ, et al. Among authors: loureiro a. Autophagy. 2021 Dec;17(12):4119-4140. doi: 10.1080/15548627.2021.1904489. Epub 2021 May 24. Autophagy. 2021. PMID: 34024231 Free PMC article.
Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets.
Tshilenge KT, Aguirre CG, Bons J, Gerencser AA, Basisty N, Song S, Rose J, Lopez-Ramirez A, Naphade S, Loureiro A, Battistoni E, Milani M, Wehrfritz C, Holtz A, Hetz C, Mooney SD, Schilling B, Ellerby LM. Tshilenge KT, et al. Among authors: loureiro a. Mol Cell Proteomics. 2023 May;22(5):100534. doi: 10.1016/j.mcpro.2023.100534. Epub 2023 Mar 22. Mol Cell Proteomics. 2023. PMID: 36958627 Free PMC article.
Metabolism and disposition of zamicastat in rats.
Araújo F, Dória ML, Beliaev A, Kiss LE, Bonifácio MJ, Holenz J, Soares-da-Silva P, Loureiro AI. Araújo F, et al. Among authors: loureiro ai. Xenobiotica. 2024 Oct 10:1-12. doi: 10.1080/00498254.2024.2411993. Online ahead of print. Xenobiotica. 2024. PMID: 39359020
Nicotinamide riboside Induced Energy Stress and Metabolic Reprogramming in BEAS-2B Cells.
Cordeiro EWF, Marzola EL, Maekawa RS, Santos MRD, Assunção LG, Massafera MP, Oliveira J, Batista TGC, Sales MCOP, Maria-Engler SS, Di Mascio P, Medeiros MHG, Ronsein GE, Loureiro APM. Cordeiro EWF, et al. Among authors: loureiro apm. Chem Res Toxicol. 2024 Aug 19;37(8):1246-1268. doi: 10.1021/acs.chemrestox.3c00312. Epub 2024 Jul 11. Chem Res Toxicol. 2024. PMID: 38990804 Free PMC article.
298 results