Varela NM - Search Results

1

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy.

Poblete D, Bernal F, Llull G, Archiles S, Vasquez P, Chanqueo L, Soto N, Lavanderos MA, Quiñones LA, Varela NM. Poblete D, et al. Among authors: varela nm. Front Pharmacol. 2021 May 19;12:660965. doi: 10.3389/fphar.2021.660965. eCollection 2021. Front Pharmacol. 2021. PMID: 34093191 Free PMC article.

2

Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations.

Quiñones L, Berthou F, Varela N, Simon B, Gil L, Lucas D. Quiñones L, et al. Cancer Lett. 1999 Jul 1;141(1-2):167-71. doi: 10.1016/s0304-3835(99)00099-3. Cancer Lett. 1999. PMID: 10454258

3

CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people.

Quiñones L, Lucas D, Godoy J, Cáceres D, Berthou F, Varela N, Lee K, Acevedo C, Martínez L, Aguilera AM, Gil L. Quiñones L, et al. Cancer Lett. 2001 Dec 10;174(1):35-44. doi: 10.1016/s0304-3835(01)00686-3. Cancer Lett. 2001. PMID: 11675150

4

Relationship among metabolizing genes, smoking and alcohol used as modifier factors on prostate cancer risk: exploring some gene-gene and gene-environment interactions.

Cáceres DD, Iturrieta J, Acevedo C, Huidobro C, Varela N, Quiñones L. Cáceres DD, et al. Eur J Epidemiol. 2005;20(1):79-88. doi: 10.1007/s10654-004-1632-9. Eur J Epidemiol. 2005. PMID: 15756908

5

Study of cytochrome P450 2E1 and its allele variants in liver injury of nondiabetic, nonalcoholic steatohepatitis obese women.

Varela NM, Quiñones LA, Orellana M, Poniachik J, Csendes A, Smok G, Rodrigo R, Cáceres DD, Videla LA. Varela NM, et al. Biol Res. 2008;41(1):81-92. Epub 2008 Aug 21. Biol Res. 2008. PMID: 18769766 Free article.

6

Relative bioavailability study with two oral formulations of topiramate using a validated UPLC-MS/MS method.

Saavedra I, Tamayo E, Gamboa A, Sasso J, Varela N, Moreno I, Marchant D, Cáceres D, Quiñones L. Saavedra I, et al. Int J Clin Pharmacol Ther. 2010 May;48(5):342-8. doi: 10.5414/cpp48342. Int J Clin Pharmacol Ther. 2010. PMID: 20420791 Clinical Trial.

7

Bioequivalence of acenocoumarol in chilean volunteers: an open, randomized, double-blind, single-dose, 2-period, and 2-sequence crossover study for 2 oral formulations.

Sasso J, Carmona P, Quiñones L, Ortiz M, Tamayo E, Varela N, Cáceres D, Saavedra I. Sasso J, et al. Arzneimittelforschung. 2012 Aug;62(8):395-9. doi: 10.1055/s-0032-1316290. Epub 2012 Jul 6. Arzneimittelforschung. 2012. PMID: 22773430 Clinical Trial.

8

Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the chilean population: comparison with caucasian and asian populations.

Roco A, Quiñones L, Agúndez JA, García-Martín E, Squicciarini V, Miranda C, Garay J, Farfán N, Saavedra I, Cáceres D, Ibarra C, Varela N. Roco A, et al. Front Genet. 2012 Nov 2;3:229. doi: 10.3389/fgene.2012.00229. eCollection 2012. Front Genet. 2012. PMID: 23130019 Free PMC article.

9

A comparative bioavailability study of two formulations of pregabalin in healthy Chilean volunteers.

Quiñones L, Sasso J, Tamayo E, Catalán J, González JP, Escala M, Varela N, León J, Cáceres DD, Saavedra I. Quiñones L, et al. Ther Adv Chronic Dis. 2010 Jul;1(4):141-8. doi: 10.1177/2040622310379932. Ther Adv Chronic Dis. 2010. PMID: 23251735 Free PMC article.

10

Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through polymorphism analyses.

Varela N, Quiñones LA, Stojanova J, Garay J, Cáceres D, Cespedes S, Sasso J, Miranda C. Varela N, et al. Pharmacol Res. 2015 Nov;101:124-9. doi: 10.1016/j.phrs.2015.07.020. Epub 2015 Jul 23. Pharmacol Res. 2015. PMID: 26211952

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