Xie ZR - Search Results

1

Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer.

Li X, Gera L, Zhang S, Chen Y, Lou L, Wilson LM, Xie ZR, Sautto G, Liu D, Danaher A, Mamouni K, Yang Y, Du Y, Fu H, Kucuk O, Osunkoya AO, Zhou J, Wu D. Li X, et al. Among authors: xie zr. Theranostics. 2021 May 8;11(14):6873-6890. doi: 10.7150/thno.49235. eCollection 2021. Theranostics. 2021. PMID: 34093859 Free PMC article.

2

A Pilot Study of All-Computational Drug Design Protocol-From Structure Prediction to Interaction Analysis.

Wu Y, Lou L, Xie ZR. Wu Y, et al. Among authors: xie zr. Front Chem. 2020 Feb 12;8:81. doi: 10.3389/fchem.2020.00081. eCollection 2020. Front Chem. 2020. PMID: 32117898 Free PMC article.

3

Elucidating the Inhibitory Effect of Resveratrol and Its Structural Analogs on Selected Nucleotide-Related Enzymes.

Wu Y, Hsieh TC, Wu JM, Wang X, Christopher JS, Pham AH, Swaby JD, Lou L, Xie ZR. Wu Y, et al. Among authors: xie zr. Biomolecules. 2020 Aug 22;10(9):1223. doi: 10.3390/biom10091223. Biomolecules. 2020. PMID: 32842666 Free PMC article.

4

In silico identification of drug candidates against COVID-19.

Wu Y, Chang KY, Lou L, Edwards LG, Doma BK, Xie ZR. Wu Y, et al. Among authors: xie zr. Inform Med Unlocked. 2020;21:100461. doi: 10.1016/j.imu.2020.100461. Epub 2020 Oct 20. Inform Med Unlocked. 2020. PMID: 33102688 Free PMC article.

5

Polyphenols as alternative treatments of COVID-19.

Wu Y, Pegan SD, Crich D, Desrochers E, Starling EB, Hansen MC, Booth C, Nicole Mullininx L, Lou L, Chang KY, Xie ZR. Wu Y, et al. Among authors: xie zr. Comput Struct Biotechnol J. 2021;19:5371-5380. doi: 10.1016/j.csbj.2021.09.022. Epub 2021 Sep 20. Comput Struct Biotechnol J. 2021. PMID: 34567475 Free PMC article.

6

Engineering a PAM-flexible SpdCas9 variant as a universal gene repressor.

Wang J, Teng Y, Zhang R, Wu Y, Lou L, Zou Y, Li M, Xie ZR, Yan Y. Wang J, et al. Among authors: xie zr. Nat Commun. 2021 Nov 25;12(1):6916. doi: 10.1038/s41467-021-27290-9. Nat Commun. 2021. PMID: 34824292 Free PMC article.

7

Polyphenols as Potential Inhibitors of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp).

Wu Y, Crich D, Pegan SD, Lou L, Hansen MC, Booth C, Desrochers E, Mullininx LN, Starling EB, Chang KY, Xie ZR. Wu Y, et al. Among authors: xie zr. Molecules. 2021 Dec 8;26(24):7438. doi: 10.3390/molecules26247438. Molecules. 2021. PMID: 34946521 Free PMC article.

8

Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria.

Wang J, Teng Y, Gong X, Zhang J, Wu Y, Lou L, Li M, Xie ZR, Yan Y. Wang J, et al. Among authors: xie zr. Metab Eng. 2023 Jan;75:68-77. doi: 10.1016/j.ymben.2022.10.005. Epub 2022 Oct 29. Metab Eng. 2023. PMID: 36404524 Free PMC article.

9

Identifying Drug Candidates for COVID-19 with Large-Scale Drug Screening.

Wu Y, Pegan SD, Crich D, Lou L, Mullininx LN, Starling EB, Booth C, Chishom AE, Chang KY, Xie ZR. Wu Y, et al. Among authors: xie zr. Int J Mol Sci. 2023 Feb 23;24(5):4397. doi: 10.3390/ijms24054397. Int J Mol Sci. 2023. PMID: 36901828 Free PMC article.

10

Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models.

Li X, Chen Y, Bai L, Zhao R, Wu Y, Xie ZR, Wu JM, Bowen NJ, Danaher A, Cook N, Li D, Qui M, Du Y, Fu H, Osunkoya AO, Kucuk O, Wu D. Li X, et al. Among authors: xie zr. Br J Cancer. 2023 Sep;129(5):884-894. doi: 10.1038/s41416-023-02359-y. Epub 2023 Jul 20. Br J Cancer. 2023. PMID: 37474721 Free PMC article.

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