Kimura H - Search Results

1

The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers.

Kimura H, Sada R, Takada N, Harada A, Doki Y, Eguchi H, Yamamoto H, Kikuchi A. Kimura H, et al. Oncogene. 2021 Jul;40(26):4486-4502. doi: 10.1038/s41388-021-01860-z. Epub 2021 Jun 11. Oncogene. 2021. PMID: 34117362 Free PMC article.

2

CKAP4 is a Dickkopf1 receptor and is involved in tumor progression.

Kimura H, Fumoto K, Shojima K, Nojima S, Osugi Y, Tomihara H, Eguchi H, Shintani Y, Endo H, Inoue M, Doki Y, Okumura M, Morii E, Kikuchi A. Kimura H, et al. J Clin Invest. 2016 Jul 1;126(7):2689-705. doi: 10.1172/JCI84658. Epub 2016 Jun 20. J Clin Invest. 2016. PMID: 27322059 Free PMC article.

3

The Dickkopf1-cytoskeleton-associated protein 4 axis creates a novel signalling pathway and may represent a molecular target for cancer therapy.

Kikuchi A, Fumoto K, Kimura H. Kikuchi A, et al. Among authors: kimura h. Br J Pharmacol. 2017 Dec;174(24):4651-4665. doi: 10.1111/bph.13863. Epub 2017 Jul 7. Br J Pharmacol. 2017. PMID: 28514532 Free PMC article. Review.

4

Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.

Shinno N, Kimura H, Sada R, Takiguchi S, Mori M, Fumoto K, Doki Y, Kikuchi A. Shinno N, et al. Among authors: kimura h. Oncogene. 2018 Jun;37(26):3471-3484. doi: 10.1038/s41388-018-0179-2. Epub 2018 Mar 22. Oncogene. 2018. PMID: 29563607

5

p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4.

Kajiwara C, Fumoto K, Kimura H, Nojima S, Asano K, Odagiri K, Yamasaki M, Hikita H, Takehara T, Doki Y, Morii E, Kikuchi A. Kajiwara C, et al. Among authors: kimura h. Cancer Res. 2018 Nov 1;78(21):6107-6120. doi: 10.1158/0008-5472.CAN-18-1749. Epub 2018 Sep 4. Cancer Res. 2018. PMID: 30181180

6

CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy.

Kimura H, Yamamoto H, Harada T, Fumoto K, Osugi Y, Sada R, Maehara N, Hikita H, Mori S, Eguchi H, Ikawa M, Takehara T, Kikuchi A. Kimura H, et al. Clin Cancer Res. 2019 Mar 15;25(6):1936-1947. doi: 10.1158/1078-0432.CCR-18-2124. Epub 2019 Jan 4. Clin Cancer Res. 2019. PMID: 30610103

7

Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth.

Harada T, Matsumoto S, Hirota S, Kimura H, Fujii S, Kasahara Y, Gon H, Yoshida T, Itoh T, Haraguchi N, Mizushima T, Noda T, Eguchi H, Nojima S, Morii E, Fukumoto T, Obika S, Kikuchi A. Harada T, et al. Among authors: kimura h. Mol Cancer Ther. 2019 Mar;18(3):602-612. doi: 10.1158/1535-7163.MCT-18-0824. Epub 2019 Jan 15. Mol Cancer Ther. 2019. PMID: 30647122

8

Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6.

Sada R, Kimura H, Fukata Y, Fukata M, Yamamoto H, Kikuchi A. Sada R, et al. Among authors: kimura h. Sci Signal. 2019 Nov 19;12(608):eaat9519. doi: 10.1126/scisignal.aat9519. Sci Signal. 2019. PMID: 31744930

9

DKK1-CKAP4 signal axis promotes hepatocellular carcinoma aggressiveness.

Iguchi K, Sada R, Matsumoto S, Kimura H, Zen Y, Akita M, Gon H, Fukumoto T, Kikuchi A. Iguchi K, et al. Among authors: kimura h. Cancer Sci. 2023 May;114(5):2063-2077. doi: 10.1111/cas.15743. Epub 2023 Mar 9. Cancer Sci. 2023. PMID: 36718957 Free PMC article.

10

CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer.

Nagoya A, Sada R, Kimura H, Yamamoto H, Morishita K, Miyoshi E, Morii E, Shintani Y, Kikuchi A. Nagoya A, et al. Among authors: kimura h. Transl Lung Cancer Res. 2023 Mar 31;12(3):408-426. doi: 10.21037/tlcr-22-571. Epub 2023 Mar 17. Transl Lung Cancer Res. 2023. PMID: 37057110 Free PMC article.

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