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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Robertson CC, Inshaw JRJ, Onengut-Gumuscu S, Chen WM, Santa Cruz DF, Yang H, Cutler AJ, Crouch DJM, Farber E, Bridges SL Jr, Edberg JC, Kimberly RP, Buckner JH, Deloukas P, Divers J, Dabelea D, Lawrence JM, Marcovina S, Shah AS, Greenbaum CJ, Atkinson MA, Gregersen PK, Oksenberg JR, Pociot F, Rewers MJ, Steck AK, Dunger DB; Type 1 Diabetes Genetics Consortium; Wicker LS, Concannon P, Todd JA, Rich SS. Robertson CC, et al. Among authors: oksenberg jr. Nat Genet. 2021 Jul;53(7):962-971. doi: 10.1038/s41588-021-00880-5. Epub 2021 Jun 14. Nat Genet. 2021. PMID: 34127860 Free PMC article.
Cytokine gene polymorphism in human disease: on-line databases.
Bidwell J, Keen L, Gallagher G, Kimberly R, Huizinga T, McDermott MF, Oksenberg J, McNicholl J, Pociot F, Hardt C, D'Alfonso S. Bidwell J, et al. Genes Immun. 1999 Sep;1(1):3-19. doi: 10.1038/sj.gene.6363645. Genes Immun. 1999. PMID: 11197303 Review.
Genomics and new targets for multiple sclerosis.
Baranzini SE, Oksenberg JR. Baranzini SE, et al. Among authors: oksenberg jr. Pharmacogenomics. 2005 Mar;6(2):151-61. doi: 10.1517/14622416.6.2.151. Pharmacogenomics. 2005. PMID: 15882133 Review.
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis.
Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL; Multiple Sclerosis Genetics Group. Gregory SG, et al. Among authors: oksenberg jr. Nat Genet. 2007 Sep;39(9):1083-91. doi: 10.1038/ng2103. Epub 2007 Jul 29. Nat Genet. 2007. PMID: 17660817
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.
Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S; International Multiple Sclerosis Genetics Consortium; De Jager PL, Wicker LS, Todd JA, Hafler DA. Maier LM, et al. Among authors: oksenberg jr. PLoS Genet. 2009 Jan;5(1):e1000322. doi: 10.1371/journal.pgen.1000322. Epub 2009 Jan 2. PLoS Genet. 2009. PMID: 19119414 Free PMC article.
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.
Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S; Wellcome Trust Case-Control Consortium (WTCCC); Compston A. Ban M, et al. Among authors: oksenberg jr. Eur J Hum Genet. 2009 Oct;17(10):1309-13. doi: 10.1038/ejhg.2009.41. Epub 2009 Mar 18. Eur J Hum Genet. 2009. PMID: 19293837 Free PMC article.
Copy number variation in African Americans.
McElroy JP, Nelson MR, Caillier SJ, Oksenberg JR. McElroy JP, et al. Among authors: oksenberg jr. BMC Genet. 2009 Mar 24;10:15. doi: 10.1186/1471-2156-10-15. BMC Genet. 2009. PMID: 19317893 Free PMC article.
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.
Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF. Baranzini SE, et al. Among authors: oksenberg jr. Nature. 2010 Apr 29;464(7293):1351-6. doi: 10.1038/nature08990. Nature. 2010. PMID: 20428171 Free PMC article.
Refining the association of MHC with multiple sclerosis in African Americans.
McElroy JP, Cree BA, Caillier SJ, Gregersen PK, Herbert J, Khan OA, Freudenberg J, Lee A, Bridges SL Jr, Hauser SL, Oksenberg JR, Gourraud PA. McElroy JP, et al. Among authors: oksenberg jr. Hum Mol Genet. 2010 Aug 1;19(15):3080-8. doi: 10.1093/hmg/ddq197. Epub 2010 May 12. Hum Mol Genet. 2010. PMID: 20466734 Free PMC article.
317 results