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p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.
Allen JD, Jaffer ZM, Park SJ, Burgin S, Hofmann C, Sells MA, Chen S, Derr-Yellin E, Michels EG, McDaniel A, Bessler WK, Ingram DA, Atkinson SJ, Travers JB, Chernoff J, Clapp DW. Allen JD, et al. Among authors: bessler wk. Blood. 2009 Mar 19;113(12):2695-705. doi: 10.1182/blood-2008-06-160861. Epub 2009 Jan 5. Blood. 2009. PMID: 19124833 Free PMC article.
Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo.
Li F, Downing BD, Smiley LC, Mund JA, Distasi MR, Bessler WK, Sarchet KN, Hinds DM, Kamendulis LM, Hingtgen CM, Case J, Clapp DW, Conway SJ, Stansfield BK, Ingram DA Jr. Li F, et al. Among authors: bessler wk. Circulation. 2014 Mar 18;129(11):1213-24. doi: 10.1161/CIRCULATIONAHA.113.006320. Epub 2013 Dec 26. Circulation. 2014. PMID: 24370551 Free PMC article.
Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1-Deficient Mice.
Burks CA, Rhodes SD, Bessler WK, Chen S, Smith A, Gehlhausen JR, Hawley ET, Jiang L, Li X, Yuan J, Lu Q, Jacobsen M, Sandusky GE, Jones DR, Clapp DW, Blakeley JO. Burks CA, et al. Among authors: bessler wk. Mol Cancer Ther. 2019 Dec;18(12):2321-2330. doi: 10.1158/1535-7163.MCT-19-0123. Epub 2019 Sep 16. Mol Cancer Ther. 2019. PMID: 31527226 Free PMC article.
Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1.
Armstrong AE, Rhodes SD, Smith A, Chen S, Bessler W, Ferguson MJ, Jiang L, Li X, Yuan J, Yang X, Yang FC, Robertson KA, Ingram DA, Blakeley JO, Clapp DW. Armstrong AE, et al. Pediatr Blood Cancer. 2020 Aug;67(8):e28372. doi: 10.1002/pbc.28372. Epub 2020 May 27. Pediatr Blood Cancer. 2020. PMID: 32459399 Free PMC article.
25 results