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Page 1
Pharmacokinetic-pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies.
Bauer S, Demetri GD, Halilovic E, Dummer R, Meille C, Tan DSW, Guerreiro N, Jullion A, Ferretti S, Jeay S, Van Bree L, Hourcade-Potelleret F, Wuerthner JU, Fabre C, Cassier PA. Bauer S, et al. Among authors: guerreiro n. Br J Cancer. 2021 Aug;125(5):687-698. doi: 10.1038/s41416-021-01444-4. Epub 2021 Jun 17. Br J Cancer. 2021. PMID: 34140638 Free PMC article. Clinical Trial.
Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201.
Jeay S, Ferretti S, Holzer P, Fuchs J, Chapeau EA, Wartmann M, Sterker D, Romanet V, Murakami M, Kerr G, Durand EY, Gaulis S, Cortes-Cros M, Ruetz S, Stachyra TM, Kallen J, Furet P, Würthner J, Guerreiro N, Halilovic E, Jullion A, Kauffmann A, Kuriakose E, Wiesmann M, Jensen MR, Hofmann F, Sellers WR. Jeay S, et al. Among authors: guerreiro n. Cancer Res. 2018 Nov 1;78(21):6257-6267. doi: 10.1158/0008-5472.CAN-18-0338. Epub 2018 Aug 22. Cancer Res. 2018. PMID: 30135191 Clinical Trial.
Results from a First-in-Human Phase I Study of Siremadlin (HDM201) in Patients with Advanced Wild-Type TP53 Solid Tumors and Acute Leukemia.
Stein EM, DeAngelo DJ, Chromik J, Chatterjee M, Bauer S, Lin CC, Suarez C, de Vos F, Steeghs N, Cassier PA, Tai D, Kiladjian JJ, Yamamoto N, Mous R, Esteve J, Minami H, Ferretti S, Guerreiro N, Meille C, Radhakrishnan R, Pereira B, Mariconti L, Halilovic E, Fabre C, Carpio C. Stein EM, et al. Among authors: guerreiro n. Clin Cancer Res. 2022 Mar 1;28(5):870-881. doi: 10.1158/1078-0432.CCR-21-1295. Clin Cancer Res. 2022. PMID: 34862243 Free PMC article. Clinical Trial.
Co-Targeting of MDM2 and CDK4/6 with Siremadlin and Ribociclib for the Treatment of Patients with Well-Differentiated or Dedifferentiated Liposarcoma: Results from a Proof-of-Concept, Phase Ib Study.
Abdul Razak AR, Bauer S, Suarez C, Lin CC, Quek R, Hütter-Krönke ML, Cubedo R, Ferretti S, Guerreiro N, Jullion A, Orlando EJ, Clementi G, Sand Dejmek J, Halilovic E, Fabre C, Blay JY, Italiano A. Abdul Razak AR, et al. Among authors: guerreiro n. Clin Cancer Res. 2022 Mar 15;28(6):1087-1097. doi: 10.1158/1078-0432.CCR-21-1291. Clin Cancer Res. 2022. PMID: 34921024 Clinical Trial.
A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer.
Kuemmel S, Campone M, Loirat D, Lopez RL, Beck JT, De Laurentiis M, Im SA, Kim SB, Kwong A, Steger GG, Adelantado EZ, Duhoux FP, Greil R, Kuter I, Lu YS, Tibau A, Özgüroğlu M, Scholz CW, Singer CF, Vega E, Wimberger P, Zamagni C, Couillebault XM, Fan L, Guerreiro N, Mataraza J, Sand-Dejmek J, Chan A. Kuemmel S, et al. Among authors: guerreiro n. Clin Cancer Res. 2022 Jan 1;28(1):106-115. doi: 10.1158/1078-0432.CCR-20-3955. Epub 2021 Oct 6. Clin Cancer Res. 2022. PMID: 34615719 Clinical Trial.
Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use.
Gomes-Silva J, Pinho MD, Friães A, Ramirez M, Melo-Cristino J, Silva-Costa C; Portuguese Group for the Study of Streptococcal Infections; Portuguese Study Group of Invasive Pneumococcal Disease of the Pediatric Infectious Disease Society. Gomes-Silva J, et al. Pneumonia (Nathan). 2024 Nov 25;16(1):26. doi: 10.1186/s41479-024-00151-x. Pneumonia (Nathan). 2024. PMID: 39582053 Free PMC article.
Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023.
Gouveia C, Bajanca-Lavado MP, Mamede R, Araújo Carvalho A, Rodrigues F, Melo-Cristino J, Ramirez M, Friães A; Portuguese Group for the Study of Streptococcal Infections; Portuguese Study Group of Pediatric Invasive Streptococcal Disease; Portuguese Study Group of Paediatric Invasive Streptococcal Disease. Gouveia C, et al. Euro Surveill. 2023 Sep;28(36):2300427. doi: 10.2807/1560-7917.ES.2023.28.36.2300427. Euro Surveill. 2023. PMID: 37676143 Free PMC article.
AIMSurv: First pan-European harmonized surveillance of Aedes invasive mosquito species of relevance for human vector-borne diseases.
Miranda MÁ, Barceló C, Arnoldi D, Augsten X, Bakran-Lebl K, Balatsos G, Bengoa M, Bindler P, Boršová K, Bourquia M, Bravo-Barriga D, Čabanová V, Caputo B, Christou M, Delacour S, Eritja R, Fassi-Fihri O, Ferraguti M, Flacio E, Frontera E, Fuehrer HP, García-Pérez AL, Georgiades P, Gewehr S, Goiri F, González MA, Gschwind M, Gutiérrez-López R, Horváth C, Ibáñez-Justicia A, Jani V, Kadriaj P, Kalan K, Kavran M, Klobucar A, Kurucz K, Lucientes J, Lühken R, Magallanes S, Marini G, Martinou AF, Michelutti A, Mihalca AD, Montalvo T, Montarsi F, Mourelatos S, Muja-Bajraktari N, Müller P, Notarides G, Osório HC, Oteo JA, Oter K, Pajović I, Palmer JRB, Petrinic S, Răileanu C, Ries C, Rogozi E, Ruiz-Arrondo I, Sanpera-Calbet I, Sekulić N, Sevim K, Sherifi K, Silaghi C, Silva M, Sokolovska N, Soltész Z, Sulesco T, Šušnjar J, Teekema S, Valsecchi A, Vasquez MI, Velo E, Michaelakis A, Wint W, Petrić D, Schaffner F, Della Torre A; Consortium AIM-COST/AIM-Surv. Miranda MÁ, et al. GigaByte. 2022 May 31;2022:gigabyte57. doi: 10.46471/gigabyte.57. eCollection 2022. GigaByte. 2022. PMID: 36824512 Free PMC article.
A Practical Guide to Genitourinary Trauma.
Leite C, Guerreiro N, Camerin GR, Alves I, Oliveira B, Nastri M, Jayanthi SK, Horvat JV, Cavalcante Viana PC, Horvat N. Leite C, et al. Among authors: guerreiro n. Radiographics. 2021 Jan-Feb;41(1):96-97. doi: 10.1148/rg.2021200110. Radiographics. 2021. PMID: 33411613 No abstract available.
43 results