Bhardwaj T - Search Results

1

A novel inhibitor L755507 efficiently blocks c-Myc-MAX heterodimerization and induces apoptosis in cancer cells.

Singh A, Kumar A, Kumar P, Nayak N, Bhardwaj T, Giri R, Garg N. Singh A, et al. Among authors: bhardwaj t. J Biol Chem. 2021 Jul;297(1):100903. doi: 10.1016/j.jbc.2021.100903. Epub 2021 Jun 23. J Biol Chem. 2021. PMID: 34157284 Free PMC article.

2

Japanese encephalitis virus - exploring the dark proteome and disorder-function paradigm.

Bhardwaj T, Saumya KU, Kumar P, Sharma N, Gadhave K, Uversky VN, Giri R. Bhardwaj T, et al. FEBS J. 2020 Sep;287(17):3751-3776. doi: 10.1111/febs.15427. Epub 2020 Jun 18. FEBS J. 2020. PMID: 32473054 Free article.

3

Understanding COVID-19 via comparative analysis of dark proteomes of SARS-CoV-2, human SARS and bat SARS-like coronaviruses.

Giri R, Bhardwaj T, Shegane M, Gehi BR, Kumar P, Gadhave K, Oldfield CJ, Uversky VN. Giri R, et al. Among authors: bhardwaj t. Cell Mol Life Sci. 2021 Feb;78(4):1655-1688. doi: 10.1007/s00018-020-03603-x. Epub 2020 Jul 25. Cell Mol Life Sci. 2021. PMID: 32712910 Free PMC article.

4

Exploring the SARS-CoV-2 structural proteins for multi-epitope vaccine development: an in-silico approach.

Kumar A, Kumar P, Saumya KU, Kapuganti SK, Bhardwaj T, Giri R. Kumar A, et al. Among authors: bhardwaj t. Expert Rev Vaccines. 2020 Sep;19(9):887-898. doi: 10.1080/14760584.2020.1813576. Epub 2020 Sep 9. Expert Rev Vaccines. 2020. PMID: 32815406 Free PMC article.

5

Zika virus NS4A N-Terminal region (1-48) acts as a cofactor for inducing NTPase activity of NS3 helicase but not NS3 protease.

Kumar D, Kumar A, Bhardwaj T, Giri R. Kumar D, et al. Among authors: bhardwaj t. Arch Biochem Biophys. 2020 Nov 30;695:108631. doi: 10.1016/j.abb.2020.108631. Epub 2020 Oct 17. Arch Biochem Biophys. 2020. PMID: 33080173

6

Reprofiling of approved drugs against SARS-CoV-2 main protease: an in-silico study.

Kumar P, Bhardwaj T, Kumar A, Gehi BR, Kapuganti SK, Garg N, Nath G, Giri R. Kumar P, et al. Among authors: bhardwaj t. J Biomol Struct Dyn. 2022 Apr;40(7):3170-3184. doi: 10.1080/07391102.2020.1845976. Epub 2020 Nov 12. J Biomol Struct Dyn. 2022. PMID: 33179586 Free PMC article.

7

Salvianolic acid B noncovalently interacts with disordered c-Myc: a computational and spectroscopic-based study.

Singh A, Kumar A, Kumar P, Bhardwaj T, Giri R, Garg N. Singh A, et al. Among authors: bhardwaj t. Future Med Chem. 2021 Aug;13(16):1341-1352. doi: 10.4155/fmc-2021-0087. Epub 2021 Jun 11. Future Med Chem. 2021. PMID: 34114895

8

Conformational dynamics of 13 amino acids long NSP11 of SARS-CoV-2 under membrane mimetics and different solvent conditions.

Gadhave K, Kumar P, Kumar A, Bhardwaj T, Garg N, Giri R. Gadhave K, et al. Among authors: bhardwaj t. Microb Pathog. 2021 Sep;158:105041. doi: 10.1016/j.micpath.2021.105041. Epub 2021 Jun 10. Microb Pathog. 2021. PMID: 34119626 Free PMC article.

9

One microsecond MD simulations of the SARS-CoV-2 main protease and hydroxychloroquine complex reveal the intricate nature of binding.

Kumar P, Bhardwaj T, Kumar A, Garg N, Giri R. Kumar P, et al. Among authors: bhardwaj t. J Biomol Struct Dyn. 2022;40(21):10763-10770. doi: 10.1080/07391102.2021.1948447. Epub 2021 Jul 29. J Biomol Struct Dyn. 2022. PMID: 34320905

10

Microsecond simulations and CD spectroscopy reveals the intrinsically disordered nature of SARS-CoV-2 spike-C-terminal cytoplasmic tail (residues 1242-1273) in isolation.

Kumar P, Bhardwaj T, Garg N, Giri R. Kumar P, et al. Among authors: bhardwaj t. Virology. 2022 Jan;566:42-55. doi: 10.1016/j.virol.2021.11.005. Epub 2021 Nov 27. Virology. 2022. PMID: 34864296 Free PMC article.

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