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A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: dong h. bioRxiv [Preprint]. 2021 Jun 17:2021.06.16.448754. doi: 10.1101/2021.06.16.448754. bioRxiv. 2021. Update in: J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818 PMID: 34159330 Free PMC article. Updated. Preprint.
Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease.
Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A. Pillai PS, et al. Among authors: dong h. Science. 2016 Apr 22;352(6284):463-6. doi: 10.1126/science.aaf3926. Science. 2016. PMID: 27102485 Free PMC article.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Israelow B, et al. Among authors: dong h. bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. Update in: J Exp Med. 2020 Dec 7;217(12):e20201241. doi: 10.1084/jem.20201241 PMID: 32577647 Free PMC article. Updated. Preprint.
A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Gomez-Calvo ML, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: dong h. J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818. Epub 2021 Nov 10. J Exp Med. 2022. PMID: 34757384 Free PMC article.
Endogenous Retroviruses Provide Protection Against Vaginal HSV-2 Disease.
Jayewickreme R, Mao T, Philbrick W, Kong Y, Treger RS, Lu P, Rakib T, Dong H, Dang-Lawson M, Guild WA, Lau TJ, Iwasaki A, Tokuyama M. Jayewickreme R, et al. Among authors: dong h. Front Immunol. 2022 Jan 4;12:758721. doi: 10.3389/fimmu.2021.758721. eCollection 2021. Front Immunol. 2022. PMID: 35058919 Free PMC article.
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