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Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators.
Huppertsberg A, Kaps L, Zhong Z, Schmitt S, Stickdorn J, Deswarte K, Combes F, Czysch C, De Vrieze J, Kasmi S, Choteschovsky N, Klefenz A, Medina-Montano C, Winterwerber P, Chen C, Bros M, Lienenklaus S, Sanders NN, Koynov K, Schuppan D, Lambrecht BN, David SA, De Geest BG, Nuhn L. Huppertsberg A, et al. Among authors: deswarte k. J Am Chem Soc. 2021 Jul 7;143(26):9872-9883. doi: 10.1021/jacs.1c03772. Epub 2021 Jun 24. J Am Chem Soc. 2021. PMID: 34166595 Free PMC article.
pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation.
Nuhn L, Vanparijs N, De Beuckelaer A, Lybaert L, Verstraete G, Deswarte K, Lienenklaus S, Shukla NM, Salyer AC, Lambrecht BN, Grooten J, David SA, De Koker S, De Geest BG. Nuhn L, et al. Among authors: deswarte k. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8098-103. doi: 10.1073/pnas.1600816113. Epub 2016 Jul 5. Proc Natl Acad Sci U S A. 2016. PMID: 27382168 Free PMC article.
The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome.
Pyfferoen L, Brabants E, Everaert C, De Cabooter N, Heyns K, Deswarte K, Vanheerswynghels M, De Prijck S, Waegemans G, Dullaers M, Hammad H, De Wever O, Mestdagh P, Vandesompele J, Lambrecht BN, Vermaelen KY. Pyfferoen L, et al. Among authors: deswarte k. Oncoimmunology. 2016 Nov 8;6(1):e1253655. doi: 10.1080/2162402X.2016.1253655. eCollection 2017. Oncoimmunology. 2016. PMID: 28197369 Free PMC article.
Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide.
Udhayakumar VK, De Beuckelaer A, McCaffrey J, McCrudden CM, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S. Udhayakumar VK, et al. Among authors: deswarte k. Adv Healthc Mater. 2017 Jul;6(13). doi: 10.1002/adhm.201601412. Epub 2017 Apr 24. Adv Healthc Mater. 2017. PMID: 28436620
52 results