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Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis.
Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Samuel M, et al. Among authors: adda cg. Nat Commun. 2021 Jun 24;12(1):3950. doi: 10.1038/s41467-021-24273-8. Nat Commun. 2021. PMID: 34168137 Free PMC article.
Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling.
Zhao K, Bleackley M, Chisanga D, Gangoda L, Fonseka P, Liem M, Kalra H, Al Saffar H, Keerthikumar S, Ang CS, Adda CG, Jiang L, Yap K, Poon IK, Lock P, Bulone V, Anderson M, Mathivanan S. Zhao K, et al. Among authors: adda cg. Commun Biol. 2019 Aug 9;2:305. doi: 10.1038/s42003-019-0538-8. eCollection 2019. Commun Biol. 2019. PMID: 31428693 Free PMC article.
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S. Keerthikumar S, et al. Among authors: adda cg. Oncotarget. 2015 Jun 20;6(17):15375-96. doi: 10.18632/oncotarget.3801. Oncotarget. 2015. PMID: 25944692 Free PMC article.
Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells.
Kalra H, Gangoda L, Fonseka P, Chitti SV, Liem M, Keerthikumar S, Samuel M, Boukouris S, Al Saffar H, Collins C, Adda CG, Ang CS, Mathivanan S. Kalra H, et al. Among authors: adda cg. J Extracell Vesicles. 2019 Nov 15;8(1):1690217. doi: 10.1080/20013078.2019.1690217. eCollection 2019. J Extracell Vesicles. 2019. PMID: 31819794 Free PMC article.
33 results