Granzier H - Search Results

1

Further progress in understanding of myofibrillar function in health and disease.

Cremo C, Moss RL, Granzier H. Cremo C, et al. Among authors: granzier h. J Gen Physiol. 2021 Jul 5;153(7):e202112972. doi: 10.1085/jgp.202112972. Epub 2021 Jun 25. J Gen Physiol. 2021. PMID: 34170286 Free PMC article.

2

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.

Sheikh F, Ouyang K, Campbell SG, Lyon RC, Chuang J, Fitzsimons D, Tangney J, Hidalgo CG, Chung CS, Cheng H, Dalton ND, Gu Y, Kasahara H, Ghassemian M, Omens JH, Peterson KL, Granzier HL, Moss RL, McCulloch AD, Chen J. Sheikh F, et al. Among authors: granzier hl. J Clin Invest. 2012 Apr;122(4):1209-21. doi: 10.1172/JCI61134. Epub 2012 Mar 19. J Clin Invest. 2012. PMID: 22426213 Free PMC article.

3

Removal of immunoglobulin-like domains from titin's spring segment alters titin splicing in mouse skeletal muscle and causes myopathy.

Buck D, Smith JE 3rd, Chung CS, Ono Y, Sorimachi H, Labeit S, Granzier HL. Buck D, et al. Among authors: granzier hl. J Gen Physiol. 2014 Feb;143(2):215-30. doi: 10.1085/jgp.201311129. J Gen Physiol. 2014. PMID: 24470489 Free PMC article.

4

Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.

Slater RE, Strom JG, Methawasin M, Liss M, Gotthardt M, Sweitzer N, Granzier HL. Slater RE, et al. J Gen Physiol. 2019 Jan 7;151(1):42-52. doi: 10.1085/jgp.201812259. Epub 2018 Dec 19. J Gen Physiol. 2019. PMID: 30567709 Free PMC article.

5

Progress on the regulation of myofibrillar function: Part 2.

Granzier HL, Moss RL. Granzier HL, et al. J Gen Physiol. 2019 May 6;151(5):609. doi: 10.1085/jgp.201912380. Epub 2019 Apr 15. J Gen Physiol. 2019. PMID: 30988060 Free PMC article.

6

The number of Z-repeats and super-repeats in nebulin greatly varies across vertebrates and scales with animal size.

Gohlke J, Tonino P, Lindqvist J, Smith JE, Granzier H. Gohlke J, et al. Among authors: granzier h. J Gen Physiol. 2021 Mar 1;153(3):e202012783. doi: 10.1085/jgp.202012783. J Gen Physiol. 2021. PMID: 33337482 Free PMC article.

7

Toward an understanding of myofibrillar function in health and disease.

Moss RL, Cremo C, Granzier HL. Moss RL, et al. J Gen Physiol. 2021 Mar 1;153(3):e202112880. doi: 10.1085/jgp.202112880. J Gen Physiol. 2021. PMID: 33620422 Free PMC article.

8

Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator.

van der Pijl RJ, van den Berg M, van de Locht M, Shen S, Bogaards SJP, Conijn S, Langlais P, Hooijman PE, Labeit S, Heunks LMA, Granzier H, Ottenheijm CAC. van der Pijl RJ, et al. Among authors: granzier h. J Gen Physiol. 2021 Jul 5;153(7):e202112925. doi: 10.1085/jgp.202112925. Epub 2021 Jun 21. J Gen Physiol. 2021. PMID: 34152365 Free PMC article.

9

Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle.

Ottenheijm CA, Fong C, Vangheluwe P, Wuytack F, Babu GJ, Periasamy M, Witt CC, Labeit S, Granzier H. Ottenheijm CA, et al. Among authors: granzier h. FASEB J. 2008 Aug;22(8):2912-9. doi: 10.1096/fj.07-104372. Epub 2008 Apr 23. FASEB J. 2008. PMID: 18434434 Free PMC article.

10

Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency.

Ottenheijm CA, Witt CC, Stienen GJ, Labeit S, Beggs AH, Granzier H. Ottenheijm CA, et al. Among authors: granzier h. Hum Mol Genet. 2009 Jul 1;18(13):2359-69. doi: 10.1093/hmg/ddp168. Epub 2009 Apr 4. Hum Mol Genet. 2009. PMID: 19346529 Free PMC article.

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