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Intact Type I Interferon Receptor Signaling Prevents Hepatocellular Necrosis but Not Encephalitis in a Dose-Dependent Manner in Rift Valley Fever Virus Infected Mice.
Michaely LM, Schuwerk L, Allnoch L, Schön K, Waltl I, Larsen PK, Pavlou A, Prajeeth CK, Rimmelzwaan GF, Becker SC, Kalinke U, Baumgärtner W, Gerhauser I. Michaely LM, et al. Among authors: larsen pk. Int J Mol Sci. 2022 Oct 18;23(20):12492. doi: 10.3390/ijms232012492. Int J Mol Sci. 2022. PMID: 36293352 Free PMC article.
The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway.
Yang X, Ali S, Zhao M, Richter L, Schäfer V, Schliehe-Diecks J, Frank M, Qi J, Larsen PK, Skerra J, Islam H, Wachtmeister T, Alter C, Huang A, Bhatia S, Köhrer K, Kirschning C, Weighardt H, Kalinke U, Kalscheuer R, Uhrberg M, Scheu S. Yang X, et al. Among authors: larsen pk. Front Immunol. 2022 Apr 8;13:856230. doi: 10.3389/fimmu.2022.856230. eCollection 2022. Front Immunol. 2022. PMID: 35464417 Free PMC article.
Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells.
Elsner C, Ponnurangam A, Kazmierski J, Zillinger T, Jansen J, Todt D, Döhner K, Xu S, Ducroux A, Kriedemann N, Malassa A, Larsen PK, Hartmann G, Barchet W, Steinmann E, Kalinke U, Sodeik B, Goffinet C. Elsner C, et al. Among authors: larsen pk. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19475-19486. doi: 10.1073/pnas.2002481117. Epub 2020 Jul 24. Proc Natl Acad Sci U S A. 2020. PMID: 32709741 Free PMC article.
Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells.
Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC. Schaupp L, et al. Among authors: larsen pk. Cell. 2020 May 28;181(5):1080-1096.e19. doi: 10.1016/j.cell.2020.04.022. Epub 2020 May 6. Cell. 2020. PMID: 32380006 Free article.
The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13.
Mulas F, Wang X, Song S, Nishanth G, Yi W, Brunn A, Larsen PK, Isermann B, Kalinke U, Barragan A, Naumann M, Deckert M, Schlüter D. Mulas F, et al. Among authors: larsen pk. Cell Mol Immunol. 2021 Jun;18(6):1512-1527. doi: 10.1038/s41423-020-0362-6. Epub 2020 Feb 5. Cell Mol Immunol. 2021. PMID: 32024978 Free PMC article.
Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection.
Borst K, Flindt S, Blank P, Larsen PK, Chhatbar C, Skerra J, Spanier J, Hirche C, König M, Alanentalo T, Hafner M, Waibler Z, Pfeffer K, Sexl V, Sutter G, Müller W, Graalmann T, Kalinke U. Borst K, et al. Among authors: larsen pk. PLoS Pathog. 2020 Feb 5;16(2):e1008279. doi: 10.1371/journal.ppat.1008279. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32023327 Free PMC article.
38 results