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Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo.
Carrington EM, Zhan Y, Brady JL, Zhang JG, Sutherland RM, Anstee NS, Schenk RL, Vikstrom IB, Delconte RB, Segal D, Huntington ND, Bouillet P, Tarlinton DM, Huang DC, Strasser A, Cory S, Herold MJ, Lew AM. Carrington EM, et al. Cell Death Differ. 2017 May;24(5):878-888. doi: 10.1038/cdd.2017.30. Epub 2017 Mar 31. Cell Death Differ. 2017. PMID: 28362427 Free PMC article.
NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.
Ju J, Chen A, Deng Y, Liu M, Wang Y, Wang Y, Nie M, Wang C, Ding H, Yao B, Gui T, Li X, Xu Z, Ma C, Song Y, Kvansakul M, Zen K, Zhang CY, Luo C, Fang M, Huang DCS, Allis CD, Tan R, Zeng CK, Wei J, Zhao Q. Ju J, et al. Among authors: huang dcs. Nat Commun. 2017 Oct 13;8(1):928. doi: 10.1038/s41467-017-00988-5. Nat Commun. 2017. PMID: 29030587 Free PMC article.
CARM1-mediated methylation of protein arginine methyltransferase 5 represses human γ-globin gene expression in erythroleukemia cells.
Nie M, Wang Y, Guo C, Li X, Wang Y, Deng Y, Yao B, Gui T, Ma C, Liu M, Wang P, Wang R, Tan R, Fang M, Chen B, He Y, Huang DCS, Ju J, Zhao Q. Nie M, et al. Among authors: huang dcs. J Biol Chem. 2018 Nov 9;293(45):17454-17463. doi: 10.1074/jbc.RA118.004028. Epub 2018 Sep 26. J Biol Chem. 2018. PMID: 30257864 Free PMC article.
Transcriptional silencing of fetal hemoglobin expression by NonO.
Li X, Chen M, Liu B, Lu P, Lv X, Zhao X, Cui S, Xu P, Nakamura Y, Kurita R, Chen B, Huang DCS, Liu DP, Liu M, Zhao Q. Li X, et al. Among authors: huang dcs. Nucleic Acids Res. 2021 Sep 27;49(17):9711-9723. doi: 10.1093/nar/gkab671. Nucleic Acids Res. 2021. PMID: 34379783 Free PMC article.
Correction to: PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling.
Yao B, Gui T, Zeng X, Deng Y, Wang Z, Wang Y, Yang D, Li Q, Xu P, Hu R, Li X, Chen B, Wang J, Zen K, Li H, Davis MJ, Herold MJ, Pan HF, Jiang ZW, Huang DCS, Liu M, Ju J, Zhao Q. Yao B, et al. Among authors: huang dcs. Genome Med. 2021 Oct 4;13(1):154. doi: 10.1186/s13073-021-00966-z. Genome Med. 2021. PMID: 34607606 Free PMC article. No abstract available.
The SMARCA4R1157W mutation facilitates chromatin remodeling and confers PRMT1/SMARCA4 inhibitors sensitivity in colorectal cancer.
Zeng X, Yao B, Liu J, Gong GW, Liu M, Li J, Pan HF, Li Q, Yang D, Lu P, Wu D, Xu P, Chen B, Chen P, Zhang M, Zen K, Jing J, Huang DCS, Chen D, Jiang ZW, Zhao Q. Zeng X, et al. Among authors: huang dcs. NPJ Precis Oncol. 2023 Mar 15;7(1):28. doi: 10.1038/s41698-023-00367-y. NPJ Precis Oncol. 2023. PMID: 36922568 Free PMC article.
214 results