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Page 1
Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency.
Sweatt AJ, Miyagawa K, Rhodes CJ, Taylor S, Del Rosario PA, Hsi A, Haddad F, Spiekerkoetter E, Bental-Roof M, Bland RD, Swietlik EM, Gräf S, Wilkins MR, Morrell NW, Nicolls MR, Rabinovitch M, Zamanian RT. Sweatt AJ, et al. Among authors: bland rd. Chest. 2021 Oct;160(4):1442-1458. doi: 10.1016/j.chest.2021.06.028. Epub 2021 Jun 26. Chest. 2021. PMID: 34181952 Free PMC article.
Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling.
Nickel NP, Spiekerkoetter E, Gu M, Li CG, Li H, Kaschwich M, Diebold I, Hennigs JK, Kim KY, Miyagawa K, Wang L, Cao A, Sa S, Jiang X, Stockstill RW, Nicolls MR, Zamanian RT, Bland RD, Rabinovitch M. Nickel NP, et al. Among authors: bland rd. Am J Respir Crit Care Med. 2015 Jun 1;191(11):1273-86. doi: 10.1164/rccm.201412-2291OC. Am J Respir Crit Care Med. 2015. PMID: 25853696 Free PMC article.
Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth.
Hilgendorff A, Parai K, Ertsey R, Juliana Rey-Parra G, Thébaud B, Tamosiuniene R, Jain N, Navarro EF, Starcher BC, Nicolls MR, Rabinovitch M, Bland RD. Hilgendorff A, et al. Among authors: bland rd. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 1;303(3):L215-27. doi: 10.1152/ajplung.00405.2011. Epub 2012 Jun 8. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22683569 Free PMC article.
Elafin Treatment Rescues EGFR-Klf4 Signaling and Lung Cell Survival in Ventilated Newborn Mice.
Alejandre Alcazar MA, Kaschwich M, Ertsey R, Preuss S, Milla C, Mujahid S, Masumi J, Khan S, Mokres LM, Tian L, Mohr J, Hirani DV, Rabinovitch M, Bland RD. Alejandre Alcazar MA, et al. Among authors: bland rd. Am J Respir Cell Mol Biol. 2018 Nov;59(5):623-634. doi: 10.1165/rcmb.2017-0332OC. Am J Respir Cell Mol Biol. 2018. PMID: 29894205 Free PMC article.
Novel notions on newborn lung disease.
Rabinovitch M, Bland R. Rabinovitch M, et al. Nat Med. 2002 Jul;8(7):664-6. doi: 10.1038/nm0702-664. Nat Med. 2002. PMID: 12091898 No abstract available.
Lung matrix and vascular remodeling in mechanically ventilated elastin haploinsufficient newborn mice.
Hilgendorff A, Parai K, Ertsey R, Navarro E, Jain N, Carandang F, Peterson J, Mokres L, Milla C, Preuss S, Alcazar MA, Khan S, Masumi J, Ferreira-Tojais N, Mujahid S, Starcher B, Rabinovitch M, Bland R. Hilgendorff A, et al. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 1;308(5):L464-78. doi: 10.1152/ajplung.00278.2014. Epub 2014 Dec 24. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25539853 Free PMC article.
Mechanical ventilation with 40% oxygen reduces pulmonary expression of genes that regulate lung development and impairs alveolar septation in newborn mice.
Bland RD, Mokres LM, Ertsey R, Jacobson BE, Jiang S, Rabinovitch M, Xu L, Shinwell ES, Zhang F, Beasley MA. Bland RD, et al. Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1099-110. doi: 10.1152/ajplung.00217.2007. Epub 2007 Aug 17. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17704187 Free article.
117 results