Höfle G - Search Results

1

N-Oxidation of Epothilone A-C and O-Acyl Rearrangement to C-19- and C-21-Substituted Epothilones.

Höfle G, Glaser N, Kiffe M, Hecht HJ, Sasse F, Reichenbach H. Höfle G, et al. Angew Chem Int Ed Engl. 1999 Jul 12;38(13-14):1971-1974. doi: 10.1002/(SICI)1521-3773(19990712)38:13/14<1971::AID-ANIE1971>3.0.CO;2-X. Angew Chem Int Ed Engl. 1999. PMID: 34182693

2

Isolation, crystal and solution structure determination, and biosynthesis of tubulysins--powerful inhibitors of tubulin polymerization from myxobacteria.

Steinmetz H, Glaser N, Herdtweck E, Sasse F, Reichenbach H, Höfle G. Steinmetz H, et al. Among authors: hofle g. Angew Chem Int Ed Engl. 2004 Sep 20;43(37):4888-92. doi: 10.1002/anie.200460147. Angew Chem Int Ed Engl. 2004. PMID: 15372566 No abstract available.

3

Discovery and development of the epothilones : a novel class of antineoplastic drugs.

Reichenbach H, Höfle G. Reichenbach H, et al. Among authors: hofle g. Drugs R D. 2008;9(1):1-10. doi: 10.2165/00126839-200809010-00001. Drugs R D. 2008. PMID: 18095749 Free PMC article. Review.

4

Maracin and Maracen: New Types of Ethynyl Vinyl Ether and α-Chloro Divinyl Ether Antibiotics from Sorangium cellulosum with Specific Activity Against Mycobacteria.

Herrmann M, Böhlendorf B, Irschik H, Reichenbach H, Höfle G. Herrmann M, et al. Among authors: hofle g. Angew Chem Int Ed Engl. 1998 May 18;37(9):1253-1255. doi: 10.1002/(SICI)1521-3773(19980518)37:9<1253::AID-ANIE1253>3.0.CO;2-T. Angew Chem Int Ed Engl. 1998. PMID: 29711239

5

Oxidative and reductive transformations of epothilone A.

Sefkow M, Kiffe M, Schummer D, Höfle G. Sefkow M, et al. Among authors: hofle g. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3025-30. doi: 10.1016/S0960-894X(98)00545-9. Bioorg Med Chem Lett. 1998. PMID: 9873669

6

Derivatization of the C12-C13 functional groups of epothilones A, B and C.

Sefkow M, Kiffe M, Höfle G. Sefkow M, et al. Among authors: hofle g. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3031-6. doi: 10.1016/S0960-894X(98)00546-0. Bioorg Med Chem Lett. 1998. PMID: 9873670

7

Studies on the biosynthesis of epothilones: the biosynthetic origin of the carbon skeleton.

Gerth K, Steinmetz H, Höfle G, Reichenbach H. Gerth K, et al. Among authors: hofle g. J Antibiot (Tokyo). 2000 Dec;53(12):1373-7. doi: 10.7164/antibiotics.53.1373. J Antibiot (Tokyo). 2000. PMID: 11217802 Free article.

8

Studies on the biosynthesis of epothilones: the PKS and Epothilone C/D monooxygenase.

Gerth K, Steinmetz H, Höfle G, Reichenbach H. Gerth K, et al. Among authors: hofle g. J Antibiot (Tokyo). 2001 Feb;54(2):144-8. doi: 10.7164/antibiotics.54.144. J Antibiot (Tokyo). 2001. PMID: 11302486 Free article.

9

New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: isolation, structure elucidation, and SAR studies.

Hardt IH, Steinmetz H, Gerth K, Sasse F, Reichenbach H, Höfle G. Hardt IH, et al. Among authors: hofle g. J Nat Prod. 2001 Jul;64(7):847-56. doi: 10.1021/np000629f. J Nat Prod. 2001. PMID: 11473410

10

Biologically active secondary metabolites from myxobacteria.

Reichenbach H, Höfle G. Reichenbach H, et al. Among authors: hofle g. Biotechnol Adv. 1993;11(2):219-77. doi: 10.1016/0734-9750(93)90042-l. Biotechnol Adv. 1993. PMID: 14545007

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