Zhang L - Search Results

1

Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.

Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, Sharrock AV, Brandon C, Park H, Kam TI, Dawson VL, Dawson TM, Shim JS, Hanes J, Ji H, Liu JO, Qian J, Ackerley DF, Rohrer B, Zack DJ, Mumm JS. Zhang L, et al. Elife. 2021 Jun 29;10:e57245. doi: 10.7554/eLife.57245. Elife. 2021. PMID: 34184634 Free PMC article.

2

Drug screening with zebrafish visual behavior identifies carvedilol as a potential treatment for an autosomal dominant form of retinitis pigmentosa.

Ganzen L, Ko MJ, Zhang M, Xie R, Chen Y, Zhang L, James R, Mumm J, van Rijn RM, Zhong W, Pang CP, Zhang M, Tsujikawa M, Leung YF. Ganzen L, et al. Among authors: zhang l, zhang m. Sci Rep. 2021 Jun 1;11(1):11432. doi: 10.1038/s41598-021-89482-z. Sci Rep. 2021. PMID: 34075074 Free PMC article.

3

NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation.

Sharrock AV, Mulligan TS, Hall KR, Williams EM, White DT, Zhang L, Emmerich K, Matthews F, Nimmagadda S, Washington S, Le KD, Meir-Levi D, Cox OL, Saxena MT, Calof AL, Lopez-Burks ME, Lander AD, Ding D, Ji H, Ackerley DF, Mumm JS. Sharrock AV, et al. Among authors: zhang l. Nat Methods. 2022 Feb;19(2):205-215. doi: 10.1038/s41592-021-01364-4. Epub 2022 Feb 7. Nat Methods. 2022. PMID: 35132245 Free PMC article.

4

ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates.

White DT, Eroglu AU, Wang G, Zhang L, Sengupta S, Ding D, Rajpurohit SK, Walker SL, Ji H, Qian J, Mumm JS. White DT, et al. Among authors: zhang l. Nat Protoc. 2016 Dec;11(12):2432-2453. doi: 10.1038/nprot.2016.142. Epub 2016 Nov 10. Nat Protoc. 2016. PMID: 27831568 Free PMC article.

5

Chemical genetics and regeneration.

Sengupta S, Zhang L, Mumm JS. Sengupta S, et al. Among authors: zhang l. Future Med Chem. 2015;7(16):2263-83. doi: 10.4155/fmc.15.137. Epub 2015 Oct 29. Future Med Chem. 2015. PMID: 26511866 Review.

6

Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration.

Unal Eroglu A, Mulligan TS, Zhang L, White DT, Sengupta S, Nie C, Lu NY, Qian J, Xu L, Pei W, Burgess SM, Saxena MT, Mumm JS. Unal Eroglu A, et al. Among authors: zhang l. Front Cell Dev Biol. 2018 Aug 21;6:88. doi: 10.3389/fcell.2018.00088. eCollection 2018. Front Cell Dev Biol. 2018. PMID: 30186835 Free PMC article.

7

A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration.

Zhang L, Xiang L, Liu Y, Venkatraman P, Chong L, Cho J, Bonilla S, Jin ZB, Pang CP, Ko KM, Ma P, Zhang M, Leung YF. Zhang L, et al. Among authors: zhang m. PLoS One. 2016 Mar 1;11(3):e0149663. doi: 10.1371/journal.pone.0149663. eCollection 2016. PLoS One. 2016. PMID: 26930483 Free PMC article.

8

Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinas.

Hensley MR, Emran F, Bonilla S, Zhang L, Zhong W, Grosu P, Dowling JE, Leung YF. Hensley MR, et al. Among authors: zhang l. BMC Dev Biol. 2011 Jul 14;11:45. doi: 10.1186/1471-213X-11-45. BMC Dev Biol. 2011. PMID: 21756345 Free PMC article.

9

Expression profiling of the retina of pde6c, a zebrafish model of retinal degeneration.

Zhang L, Zhang X, Zhang G, Pang CP, Leung YF, Zhang M, Zhong W. Zhang L, et al. Among authors: zhang m, zhang g, zhang x. Sci Data. 2017 Dec 12;4:170182. doi: 10.1038/sdata.2017.182. Sci Data. 2017. PMID: 29231925 Free PMC article.

10

Microdissection of zebrafish embryonic eye tissues.

Zhang L, Leung YF. Zhang L, et al. J Vis Exp. 2010 Jun 27;(40):2028. doi: 10.3791/2028. J Vis Exp. 2010. PMID: 20613711 Free PMC article.

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