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Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system.
Zhang JZ, Yeh HW, Walls AC, Wicky BIM, Sprouse K, VanBlargan LA, Treger R, Quijano-Rubio A, Pham MN, Kraft JC, Haydon IC, Yang W, DeWitt M, Chow C, Carter L, Wener MH, Stewart L, Veesler D, Diamond MS, Baker D. Zhang JZ, et al. Among authors: pham mn. bioRxiv [Preprint]. 2021 Jun 22:2021.06.22.449355. doi: 10.1101/2021.06.22.449355. bioRxiv. 2021. Update in: Nat Biotechnol. 2022 Sep;40(9):1336-1340. doi: 10.1038/s41587-022-01280-8. PMID: 34189528 Free PMC article. Updated. Preprint.
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.
Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, Zepeda SK, Starr T, Hsieh CL, Fiala B, Wrenn S, Pettie D, Sydeman C, Johnson M, Blackstone A, Ravichandran R, Ogohara C, Carter L, Tilles SW, Rappuoli R, O'Hagan DT, Van Der Most R, Van Voorhis WC, McLellan JS, Kleanthous H, Sheahan TP, Fuller DH, Villinger F, Bloom J, Pulendran B, Baric R, King N, Veesler D. Walls AC, et al. Among authors: pham mn. bioRxiv [Preprint]. 2021 Mar 16:2021.03.15.435528. doi: 10.1101/2021.03.15.435528. bioRxiv. 2021. Update in: Cell. 2021 Oct 14;184(21):5432-5447.e16. doi: 10.1016/j.cell.2021.09.015. PMID: 33758839 Free PMC article. Updated. Preprint.
Combinatorial immune refocusing within the influenza hemagglutinin head elicits cross-neutralizing antibody responses.
Dosey A, Ellis D, Boyoglu-Barnum S, Syeda H, Saunders M, Watson M, Kraft JC, Pham MN, Guttman M, Lee KK, Kanekiyo M, King NP. Dosey A, et al. Among authors: pham mn. bioRxiv [Preprint]. 2023 May 24:2023.05.23.541996. doi: 10.1101/2023.05.23.541996. bioRxiv. 2023. Update in: Cell Rep. 2023 Dec 26;42(12):113553. doi: 10.1016/j.celrep.2023.113553. PMID: 37292967 Free PMC article. Updated. Preprint.
Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens.
Miranda MC, Kepl E, Navarro MJ, Chen C, Johnson M, Sprouse KR, Stewart C, Palser A, Valdez A, Pettie D, Sydeman C, Ogohara C, Kraft JC, Pham M, Murphy M, Wrenn S, Fiala B, Ravichandran R, Ellis D, Carter L, Corti D, Kellam P, Lee K, Walls AC, Veesler D, King NP. Miranda MC, et al. NPJ Vaccines. 2024 Oct 8;9(1):184. doi: 10.1038/s41541-024-00982-1. NPJ Vaccines. 2024. PMID: 39379400 Free PMC article.
Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases.
Gardell JL, Maurer ME, Childs MM, Pham MN, Meengs B, Julien SH, Tan C, Boster DR, Quach P, Therriault JH, Hermansky G, Patton DT, Bowser J, Chen A, Morgan NN, Gilbertson EA, Bogatzki L, Encarnacion K, McMahan CJ, Crane CA, Swiderek KM. Gardell JL, et al. Among authors: pham mn. Front Immunol. 2024 Nov 4;15:1452537. doi: 10.3389/fimmu.2024.1452537. eCollection 2024. Front Immunol. 2024. PMID: 39559361 Free PMC article.
94 results