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Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.
Kurogochi M, Mori M, Osumi K, Tojino M, Sugawara S, Takashima S, Hirose Y, Tsukimura W, Mizuno M, Amano J, Matsuda A, Tomita M, Takayanagi A, Shoda S, Shirai T. Kurogochi M, et al. Among authors: osumi k. PLoS One. 2015 Jul 22;10(7):e0132848. doi: 10.1371/journal.pone.0132848. eCollection 2015. PLoS One. 2015. PMID: 26200113 Free PMC article.
Glycoside hydrolase family 89 alpha-N-acetylglucosaminidase from Clostridium perfringens specifically acts on GlcNAc alpha1,4Gal beta1R at the non-reducing terminus of O-glycans in gastric mucin.
Fujita M, Tsuchida A, Hirata A, Kobayashi N, Goto K, Osumi K, Hirose Y, Nakayama J, Yamanoi T, Ashida H, Mizuno M. Fujita M, et al. Among authors: osumi k. J Biol Chem. 2011 Feb 25;286(8):6479-89. doi: 10.1074/jbc.M110.206722. Epub 2010 Dec 21. J Biol Chem. 2011. PMID: 21177247 Free PMC article.
91 results