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Pharmacological activation of mGlu5 receptors with the positive allosteric modulator VU0360172, modulates thalamic GABAergic transmission.
Celli R, Wall MJ, Santolini I, Vergassola M, Di Menna L, Mascio G, Cannella M, van Luijtelaar G, Pittaluga A, Ciruela F, Bruno V, Nicoletti F, Ngomba RT. Celli R, et al. Among authors: wall mj. Neuropharmacology. 2020 Nov 1;178:108240. doi: 10.1016/j.neuropharm.2020.108240. Epub 2020 Aug 6. Neuropharmacology. 2020. PMID: 32768418
The comparative effects of mGlu5 receptor positive allosteric modulators VU0409551 and VU0360172 on cognitive deficits and signalling in the sub-chronic PCP rat model for schizophrenia.
Brown J, Iacovelli L, Di Cicco G, Grayson B, Rimmer L, Fletcher J, Neill JC, Wall MJ, Ngomba RT, Harte M. Brown J, et al. Among authors: wall mj. Neuropharmacology. 2022 May 1;208:108982. doi: 10.1016/j.neuropharm.2022.108982. Epub 2022 Feb 10. Neuropharmacology. 2022. PMID: 35151699
225 results