Pflégr V - Search Results

1

Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity.

Pflégr V, Horváth L, Stolaříková J, Pál A, Korduláková J, Bősze S, Vinšová J, Krátký M. Pflégr V, et al. Eur J Med Chem. 2021 Nov 5;223:113668. doi: 10.1016/j.ejmech.2021.113668. Epub 2021 Jun 23. Eur J Med Chem. 2021. PMID: 34198149

2

N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors.

Krátký M, Jaklová K, Štěpánková Š, Svrčková K, Pflégr V, Vinšová J. Krátký M, et al. Among authors: pflegr v. Curr Top Med Chem. 2020;20(23):2094-2105. doi: 10.2174/1568026620666200819154722. Curr Top Med Chem. 2020. PMID: 32814530

3

Iodinated 1,2-diacylhydrazines, benzohydrazide-hydrazones and their analogues as dual antimicrobial and cytotoxic agents.

Krátký M, Konečná K, Brablíková M, Janoušek J, Pflégr V, Maixnerová J, Trejtnar F, Vinšová J. Krátký M, et al. Among authors: pflegr v. Bioorg Med Chem. 2021 Jul 1;41:116209. doi: 10.1016/j.bmc.2021.116209. Epub 2021 May 13. Bioorg Med Chem. 2021. PMID: 34015704

4

Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study.

Krátký M, Vu QA, Štěpánková Š, Maruca A, Silva TB, Ambrož M, Pflégr V, Rocca R, Svrčková K, Alcaro S, Borges F, Vinšová J. Krátký M, et al. Among authors: pflegr v. Bioorg Chem. 2021 Nov;116:105301. doi: 10.1016/j.bioorg.2021.105301. Epub 2021 Aug 28. Bioorg Chem. 2021. PMID: 34492558

5

Design and Synthesis of Highly Active Antimycobacterial Mutual Esters of 2-(2-Isonicotinoylhydrazineylidene)propanoic Acid.

Pflégr V, Maixnerová J, Stolaříková J, Pál A, Korduláková J, Trejtnar F, Vinšová J, Krátký M. Pflégr V, et al. Pharmaceuticals (Basel). 2021 Dec 14;14(12):1302. doi: 10.3390/ph14121302. Pharmaceuticals (Basel). 2021. PMID: 34959704 Free PMC article.

6

Host cell targeting of novel antimycobacterial 4-aminosalicylic acid derivatives with tuftsin carrier peptides.

Borbála Horváth L, Krátký M, Pflégr V, Méhes E, Gyulai G, Kohut G, Babiczky Á, Biri-Kovács B, Baranyai Z, Vinšová J, Bősze S. Borbála Horváth L, et al. Among authors: pflegr v. Eur J Pharm Biopharm. 2022 May;174:111-130. doi: 10.1016/j.ejpb.2022.03.009. Epub 2022 Apr 2. Eur J Pharm Biopharm. 2022. PMID: 35378278

7

5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study.

Pflégr V, Štěpánková Š, Svrčková K, Švarcová M, Vinšová J, Krátký M. Pflégr V, et al. Pharmaceuticals (Basel). 2022 Mar 25;15(4):400. doi: 10.3390/ph15040400. Pharmaceuticals (Basel). 2022. PMID: 35455397 Free PMC article.

8

Synthesis and Antimycobacterial Activity of Isoniazid Derivatives Tethered with Aliphatic Amines.

Pflégr V, Stolaříková J, Vinšová J, Krátký M. Pflégr V, et al. Curr Top Med Chem. 2022;22(32):2695-2706. doi: 10.2174/1568026622666220805152811. Curr Top Med Chem. 2022. PMID: 35929626

9

Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study.

Houngbedji NH, Štěpánková Š, Pflégr V, Svrčková K, Švarcová M, Vinšová J, Krátký M. Houngbedji NH, et al. Among authors: pflegr v. Pharmaceuticals (Basel). 2023 Jan 24;16(2):172. doi: 10.3390/ph16020172. Pharmaceuticals (Basel). 2023. PMID: 37259322 Free PMC article.

10

Novel pyrimidine-1,3,4-oxadiazole hybrids and their precursors as potential antimycobacterial agents.

Pflégr V, Stolaříková J, Pál A, Korduláková J, Krátký M. Pflégr V, et al. Future Med Chem. 2023 Jun;15(12):1049-1067. doi: 10.4155/fmc-2023-0096. Epub 2023 Aug 9. Future Med Chem. 2023. PMID: 37555280

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