Frankel A - Search Results

1

Protein arginine methyltransferase 8 modulates mitochondrial bioenergetics and neuroinflammation after hypoxic stress.

Couto E Silva A, Wu CY, Clemons GA, Acosta CH, Chen CT, Possoit HE, Citadin CT, Lee RH, Brown JI, Frankel A, Lin HW. Couto E Silva A, et al. Among authors: frankel a. J Neurochem. 2021 Nov;159(4):742-761. doi: 10.1111/jnc.15462. Epub 2021 Aug 25. J Neurochem. 2021. PMID: 34216036 Free PMC article.

2

Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4.

Lakowski TM, Frankel A. Lakowski TM, et al. Among authors: frankel a. Biochem J. 2009 Jun 26;421(2):253-61. doi: 10.1042/BJ20090268. Biochem J. 2009. PMID: 19405910

3

Sources of S-adenosyl-L-homocysteine background in measuring protein arginine N-methyltransferase activity using tandem mass spectrometry.

Lakowski TM, Frankel A. Lakowski TM, et al. Among authors: frankel a. Anal Biochem. 2010 Jan 1;396(1):158-60. doi: 10.1016/j.ab.2009.08.043. Epub 2009 Sep 3. Anal Biochem. 2010. PMID: 19733141

4

Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases.

Lakowski TM, 't Hart P, Ahern CA, Martin NI, Frankel A. Lakowski TM, et al. Among authors: frankel a. ACS Chem Biol. 2010 Nov 19;5(11):1053-63. doi: 10.1021/cb100161u. ACS Chem Biol. 2010. PMID: 20701328

5

Förster resonance energy transfer measurements of cofactor-dependent effects on protein arginine N-methyltransferase homodimerization.

Thomas D, Lakowski TM, Pak ML, Kim JJ, Frankel A. Thomas D, et al. Among authors: frankel a. Protein Sci. 2010 Nov;19(11):2141-51. doi: 10.1002/pro.492. Protein Sci. 2010. PMID: 20812326 Free PMC article.

6

A protein arginine N-methyltransferase 1 (PRMT1) and 2 heteromeric interaction increases PRMT1 enzymatic activity.

Pak ML, Lakowski TM, Thomas D, Vhuiyan MI, Hüsecken K, Frankel A. Pak ML, et al. Among authors: frankel a. Biochemistry. 2011 Sep 27;50(38):8226-40. doi: 10.1021/bi200644c. Epub 2011 Aug 29. Biochemistry. 2011. PMID: 21851090

7

Targeting protein arginine N-methyltransferases with peptide-based inhibitors: opportunities and challenges.

Vhuiyan M, Thomas D, Hossen F, Frankel A. Vhuiyan M, et al. Among authors: frankel a. Future Med Chem. 2013 Dec;5(18):2199-206. doi: 10.4155/fmc.13.184. Future Med Chem. 2013. PMID: 24261895 Review.

8

Protein arginine N-methyltransferase substrate preferences for different nη-substituted arginyl peptides.

Thomas D, Koopmans T, Lakowski TM, Kreinin H, Vhuiyan MI, Sedlock SA, Bui JM, Martin NI, Frankel A. Thomas D, et al. Among authors: frankel a. Chembiochem. 2014 Jul 21;15(11):1607-13. doi: 10.1002/cbic.201402045. Epub 2014 Jul 8. Chembiochem. 2014. PMID: 25044481

9

Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism.

Brown JI, Koopmans T, van Strien J, Martin NI, Frankel A. Brown JI, et al. Among authors: frankel a. Chembiochem. 2018 Jan 4;19(1):85-99. doi: 10.1002/cbic.201700521. Epub 2017 Nov 29. Chembiochem. 2018. PMID: 29112789

10

Evaluation of kinetic data: What the numbers tell us about PRMTs.

Frankel A, Brown JI. Frankel A, et al. Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):306-316. doi: 10.1016/j.bbapap.2018.10.010. Epub 2018 Oct 17. Biochim Biophys Acta Proteins Proteom. 2019. PMID: 30342239 Review.

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